Evidence map›Paper›PMID 39774951›Full record

ArticleAnnals of hematology2025

PEG-rhG-CSF versus rhG-CSF in supporting neutrophil recovery after induction chemotherapy for patients with newly diagnosed acute lymphoblastic leukemia.

Shumin Jin, Mengyuan Chang, Lei Feng, Yiping Hao, Wei Li, Ying Zhou, Ruinan Jia, Wěi Li, Tingting Liu, Di Zhang and 6 more

Abstract readComparative Study
In one paragraph

Article in Annals of hematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Shumin JinDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Mengyuan ChangDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Lei FengDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Yiping HaoDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Wei LiDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Ying ZhouDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Ruinan JiaDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Wěi LiDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Tingting LiuDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Di ZhangDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Huihui JiangLaboratory of Artificial Intelligence for Hematology, Qilu Hospital, Shandong University, Jinan, 250012, P.R. China.
Jingtao WangLaboratory of Artificial Intelligence for Hematology, Qilu Hospital, Shandong University, Jinan, 250012, P.R. China.
Chuanli ZhaoDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Chunyan JiDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China.
Jingjing YeDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China. yejingjing@sdu.edu.cn.
Min JiDepartment of Hematology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, 107 West Culture Road, Lixia District, Jinan, 250012, P.R. China. jimin@sdu.edu.cn.

Funding

the Distinguished Taishan Scholars in Climbing Plan tspd20210321the Distinguished Taishan Scholars Plan tstp20230653the National Natural Science Foundation of China 82270174, 82170182, 82070160
6 · The paper itself

Abstract

To compare the efficacy and safety of pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) and rhG-CSF in the recovery of neutrophils after induction therapy in ALL patients, PEG-rhG-CSF was injected subcutaneously within 24 ~ 48 h after the end of intravenous infusion of daunorubicin/idarubicin during induction chemotherapy. In rhG-CSF group, patients were given rhG-CSF. The main outcome indexes were the incidence and duration of grade 4 chemotherapy-induced-neutropenia (CIN, ANC less than 0.5 × 10

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsGranulocyte Colony-Stimulating FactorInduction ChemotherapyNeutrophilsPolyethylene GlycolsPrecursor Cell Lymphoblastic Leukemia-LymphomaAdolescentAdultDaunorubicinFemaleHumansMaleMiddle AgedNeutropeniaRecombinant ProteinsYoung AdultDaunorubicinGranulocyte Colony-Stimulating Factorpegylated granulocyte colony-stimulating factor, humanPolyethylene GlycolsRecombinant ProteinsAcute lymphoblastic leukemiaInduction chemotherapyNeutropeniaPEG-rhG-CSF

Identifiers

PMID39774951
PMCPMC11971193

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.