Evidence map›Paper›PMID 39775100›Full record

Trial reportScientific reports2025

Randomized controlled trial on effect of different routes of dexmedetomidine on Haemodynamics in patients undergoing saphenectomy under epidural anaesthesia.

Sisi Zeng, Jixiang Wan, Xuechao Li, Na Wang, Jiabei Li, Luyue Gao, Zhen Yang, Fangjun Wang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sisi Zeng *Department of Anaesthesiology, Affiliated Hospital of North Sichuan medical college, Nanchong, Sichuan, China.
Jixiang Wan *Department of Anaesthesiology, Affiliated Hospital of North Sichuan medical college, Nanchong, Sichuan, China.
Xuechao Li *Department of Anaesthesiology, People's Hospital of Chongqing Liang Jiang New Area, Chongqing, China.
Na WangDepartment of Anaesthesiology, Affiliated Hospital of North Sichuan medical college, Nanchong, Sichuan, China.
Jiabei LiDepartment of Anaesthesiology, Affiliated Hospital of North Sichuan medical college, Nanchong, Sichuan, China.
Luyue GaoDepartment of Anaesthesiology, Affiliated Hospital of North Sichuan medical college, Nanchong, Sichuan, China.
Zhen YangDepartment of Anaesthesiology, Affiliated Hospital of North Sichuan medical college, Nanchong, Sichuan, China.
Fangjun WangDepartment of Anaesthesiology, Affiliated Hospital of North Sichuan medical college, Nanchong, Sichuan, China. wfjlxy006@nsmc.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of epidural infusion of dexmedetomidine on haemodynamics is unclear. This study aimed to explore the effects of epidural or intravenous infusion of dexmedetomidine on haemodynamics during lower extremity varicose veins surgery (saphenectomy) under epidural anaesthesia. Ninety patients were randomly allocated to three groups: ED group (epidural: 0.59% ropivacaine plus 0.5 µg/kg dexmedetomidine, intravenous: normal saline), VD group (epidural: 0.59% ropivacaine plus normal saline, intravenous: 0.5 µg/kg dexmedetomidine), or NS group (epidural: 0.59% ropivacaine plus normal saline, intravenous: normal saline). The primary outcome was the systolic blood pressure (SBP) at before anaesthesia (T

Indexed as

Anesthesia, EpiduralBlood PressureDexmedetomidineHemodynamicsAdultAgedFemaleHeart RateHumansMaleMiddle AgedRopivacaineSaphenous VeinVaricose VeinsDexmedetomidineRopivacaineAdministration routesAnaesthetic effectDexmedetomidineEpidural anaesthesiaHaemodynamicsRopivacaine

Identifiers

PMID39775100
PMCPMC11706940

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.