Evidence map›Paper›PMID 39775186›Full record

ArticleHead and neck pathology2025

EWSR1::BEND2 Adenocarcinoma with Hyaline Pseudorosettes of the Trachea.

Juan J Sanchez-Ramirez, Matthew R Hoffman, John C Keech, Anthony N Snow, Andrew M Bellizzi, Anand Rajan

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PubMed Full text at PMC Publisher
In one paragraph

Article in Head and neck pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juan J Sanchez-RamirezDepartment of Otolaryngology, 200 Hawkins Drive University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA.
Matthew R HoffmanDepartment of Otolaryngology, 200 Hawkins Drive University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA.
John C KeechDepartment of Cardiothoracic Surgery, 200 Hawkins Drive University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA.
Anthony N SnowDepartment of Otolaryngology, 200 Hawkins Drive University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA.
Andrew M BellizziDepartment of Otolaryngology, 200 Hawkins Drive University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA.
Anand RajanDepartment of Otolaryngology, 200 Hawkins Drive University of Iowa Hospitals and Clinics, Iowa City, IA, 52242, USA. anand-rajand@uiowa.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the novel occurrence of a adenocarcinoma involving the trachea, with distinct solid and glandular components, in a 34-year-old patient. We illustrate its morphological and immunophenotypic features and describe the molecular finding of an EWSR1::BEND2 gene fusion detected by next-generation sequencing (NGS). We discuss the findings in comparison to BEND2-fusion associated neoplasms reported in the head and neck region in the literature to date.

Indexed as

AdenocarcinomaRNA-Binding Protein EWSTracheal NeoplasmsAdultBiomarkers, TumorHumansOncogene Proteins, FusionBiomarkers, TumorEWSR1 protein, humanOncogene Proteins, FusionRNA-Binding Protein EWSBEND2BEN domain proteinsESWR1::BEND2 FusionGene fusionSalivary gland carcinoma

Identifiers

PMID39775186
PMCPMC11707210

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.