Evidence map›Paper›PMID 39777225›Full record

ReviewFrontiers in endocrinology2024

New insights into the management of homozygous familial hypercholesterolemia patients treated with lomitapide: a single-center experience.

Gabriella Iannuzzo, Ilenia Lorenza Calcaterra, Marco Gentile, Claudia Stanzione, Francesca de Ruberto, Maria Donata di Taranto, Giovanna Cardiero, Giuliana Fortunato, Matteo Di Minno

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gabriella Iannuzzo *Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Naples, Italy.
Ilenia Lorenza Calcaterra *Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Naples, Italy.
Marco GentileDepartment of Molecular Medicine and Medical Biotechnologies, CEINGE Advanced Biotechnologies S.C. A.R.L, University of Naples Federico II, Naples, Italy.
Claudia StanzioneDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Naples, Italy.
Francesca de RubertoDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Naples, Italy.
Maria Donata di TarantoDepartment of Molecular Medicine and Medical Biotechnologies, CEINGE Advanced Biotechnologies S.C. A.R.L, University of Naples Federico II, Naples, Italy.
Giovanna CardieroDepartment of Molecular Medicine and Medical Biotechnologies, CEINGE Advanced Biotechnologies S.C. A.R.L, University of Naples Federico II, Naples, Italy.
Giuliana FortunatoDepartment of Molecular Medicine and Medical Biotechnologies, CEINGE Advanced Biotechnologies S.C. A.R.L, University of Naples Federico II, Naples, Italy.
Matteo Di MinnoDepartment of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Familial hypercholesterolemia (FH) is a genetic disease, usually with onset during childhood, characterized by elevated blood LDL cholesterol levels and potentially associated with severe cardiovascular complications. Concerning mutated genes in FH, such as

Indexed as

Anticholesteremic AgentsBenzimidazolesHomozygoteHyperlipoproteinemia Type IIAdolescentAdultFemaleHumansMaleMiddle AgedYoung AdultAnticholesteremic AgentsBenzimidazolesBMS201038HoFHhypercholesterolemialomitapidemanagementmonitoring

Identifiers

PMID39777225
PMCPMC11703714

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.