Evidence map›Paper›PMID 39777280›Full record

ReviewHealth science reports2025

The Impact of Selected Regimens of Chronic HIV-Antiretroviral Treatment on Glycemic Control Markers and Correlates: A Systematic Review and Meta-Analysis Protocol.

Mlindeli Gamede, Mbulelo Aubrey Sosibo, Nontobeko Gumede, Mluleki Luvuno

Abstract readReview
In one paragraph

Review in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mlindeli GamedeDepartment of Physiology, Faculty of Health Sciences University of Pretoria Gauteng South Africa.ORCID 0000-0001-5512-1545
Mbulelo Aubrey SosiboSchool of Laboratory Medicine and Medical Sciences, College of Health Sciences University of KwaZulu-Natal Durban South Africa.
Nontobeko GumedeDepartment of Physiology, Faculty of Health Sciences University of Pretoria Gauteng South Africa.
Mluleki LuvunoSchool of Laboratory Medicine and Medical Sciences, College of Health Sciences University of KwaZulu-Natal Durban South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Diabetes mellitus is one of the leading causes of morbidity and mortality among non-communicable diseases worldwide. The etiology of diabetes can be mainly attributed to factors such as genetic susceptibility, unhealthy diets, and chronic medications. Chronic medications such as HIV-antiretrovirals (ARVs) have been previously associated with the risks of developing metabolic complications. Hence, this protocol outlines the process for conducting a systematic review to investigate the association between chronic ARV treatment and the onset of metabolic syndrome complications. Methodology and Analysis: The studies included in the systematic review are selected according to the inclusion and exclusion criteria. These studies are searched using search engines or databases such as PUBMED, GOOGLE SCHOLAR, MEDLINE, ScienceDirect, and EMBASE DATABASE. The articles that remained after full article screening will be assessed for bias using the Downs and Black checklist, and the data will be extracted. Additionally, heterogeneity tests will be conducted using both Χ Dissemination and Registration: The findings intend to give an insight into the ARVs as a risk factor for metabolic diseases and further elaborate on the regimen that possesses a high risk between the first and second regimens. This protocol has been registered on PROSPERO Database #CRD42024521322.

Indexed as

antiretroviral therapyART and lipid profile and hyperlipidemiadiabetes mellitusdysglycemiaHIV and impaired glucose toleranceHIV‐antiretroviral regimensimpaired glucose tolerancemetabolic disease and HIV

Identifiers

PMID39777280
PMCPMC11705394

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.