SynthesisFrontiers in physiology2024
Effects of exercise on bone mass and bone metabolism in adolescents: a systematic review and meta-analysis.
Synthesis in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Outcomes From Use of the Fédération International de Football Association (FIFA) 11⁺ Program With and Without Transcranial Direct Current Stimulation in 60 Male High School Soccer Players.Medical science monitor : international medical journal of experimental and clinical research · 2026Trial
- Article
- Low-energy hip fracture in a socially withdrawn and physically inactive teenager highlighting the age-independent role of mechanical loading and nutrition: a case report.Journal of medical case reports · 2026Article
- Skeletal Age Evaluation with BAUSportJournal of functional morphology and kinesiology · 2026Article
- Socio-Demographic Associations and Frequencies of Physical Activity Participation of Autistic Adolescents Reported by Parents in Ontario, Canada.Journal of autism and developmental disorders · 2026Article
- Acute Biochemical Responses to Competitive Tournament Load in Female Handball Players: Hormonal, Inflammatory and Muscle Damage Markers.Life (Basel, Switzerland) · 2026Article
- Nonlinear association between physical activity and bone mineral density in adolescents.Pediatric research · 2026Article
- Development of the Muscular and Skeletal System During Adolescence.Advances in experimental medicine and biology · 2026Review
- Sarcopenic obesity and skeletal development in children: recent advances.Frontiers in pediatrics · 2026Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Meta-analysis was used to evaluate the effects of an exercise intervention on bone mineral content (BMC), bone mineral density (BMD), and bone metabolism in adolescents. Methods: A systematic search of PubMed, Embase, Cochrane Library, and Web of Science for RCTs on "exercise, adolescents, BMD, bone metabolism" up to 10 September 2024. Included RCTs focused on effects of exercise on BMC, BMD, and bone metabolism in 10-19 years old, with physical activity as exercise group and daily living/primal exercise as control group. Outcome metrics included lumbar spine, femoral neck, whole body BMC and BMD, bone alkaline phosphatase (BALP), procollagen type 1N-terminal propeptide (PINP), osteocalcin (OC), and type I collagen carboxy-terminal peptide (CTX). Exclusion criteria included duplicates, non-RCTs, non-adolescent studies, and non-compliance with indicators. Meta-analyses were performed using RevMan 5.4, and quality assessed by Cochrane's tool. Effect sizes were estimated using standardized mean differences ( Results: Fifteen articles with a total of 723 subjects were included. The meta-analysis showed that, compared to the control group, (i) exercise was effective in increasing adolescents' overall BMC ( Conclusion: Exercise is effective in improving overall BMC and BMD in adolescents and elevating BMC and BMD of the lumbar spine and femoral neck. Due to the limitation of the number and quality of the included studies, the above conclusions are yet to be validated by more high-quality empirical studies. Systematic Review Registration: https://www.crd.york.ac.uk/, identifier CRD42024593399.
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Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.