Evidence map›Paper›PMID 39777830›Full record

ArticleAnimal science journal = Nihon chikusan Gakkaiho

Effects of dietary supplementation of myristic acid on jejunal mucosa-associated microbiota, mucosal immunity, and growth performance of nursery pigs.

Hyunjun Choi, Gabriel Cipriano Rocha, Sung Woo Kim

Abstract read
In one paragraph

Article in Animal science journal = Nihon chikusan Gakkaiho. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hyunjun ChoiDepartment of Animal Science, North Carolina State University, Raleigh, NC, USA.ORCID https://orcid.org/0000-0002-5874-2328
Gabriel Cipriano RochaDepartment of Animal Science, North Carolina State University, Raleigh, NC, USA.ORCID https://orcid.org/0000-0001-7671-9271
Sung Woo KimDepartment of Animal Science, North Carolina State University, Raleigh, NC, USA.ORCID https://orcid.org/0000-0003-4591-1943

Funding

Coordination for the Improvement of Higher Education PersonnelGuangzhou Insighter Biotechnology Corporation, Ltd.North Carolina Agricultural Foundation 660101USDA-NIFA Hatch 02893
6 · The paper itself

Abstract

The objective of this study was to investigate the effects of myristic acid on jejunal mucosal microbiota, mucosal immunity, and growth performance of nursery pigs. Thirty-six pigs (6.6 ± 0.4 kg of body weight) were assigned to three treatments (n = 12) for 35 d in three phases: (NC) basal diet; (PC) NC + bacitracin; and (MA) NC + myristic acid compound. Pigs were euthanized to collect jejunal mucosa, jejunal tissues, and ileal digesta. The PC increased (p < 0.05) the relative abundance (RA) of Lactobacillus spp., and Bifidobacterium boum than the NC group. The MA increased (p < 0.05) RA of Bifidobacterium dentium and Megasphaera spp. than the NC group. The PC tended to decrease IL-8 (p = 0.053) and protein carbonyl (p = 0.075) whereas IgG (p = 0.051) and IL-8 (p = 0.090) in jejunal mucosa were decreased by the MA. The PC increased (p < 0.05) the villus height to crypt depth ratio than the NC group. Both bacitracin and myristic acid improved the intestinal health and growth performance of nursery pigs. Effects of bacitracin were rather immediate whereas the effects of myristic acid were obtained after a 3-week feeding.

Indexed as

DietDietary SupplementsGastrointestinal MicrobiomeImmunity, MucosalIntestinal MucosaJejunumMyristic AcidAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsBacitracinInterleukin-8SwineBacitracinInterleukin-8Myristic Acidantibioticgrowth performancemucosal immunitymyristic acidnursery pig

Identifiers

PMID39777830
PMCPMC11707569

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.