Evidence map›Paper›PMID 39779619›Full record

ArticlePharmaceutical research2025

Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy - active Phytochemicals and In Vivo Molecular Targets.

Junxuan Lü, Cheng Jiang, Joseph J Drabick, Monika Joshi, Stuthi Perimbeti

Abstract read
In one paragraph

Article in Pharmaceutical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Junxuan LüDepartment of Pharmacology, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA. junxuanlu@pennstatehealth.psu.edu.ORCID http://orcid.org/0000-0002-2354-7186
Cheng JiangDepartment of Pharmacology, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Joseph J DrabickPenn State Cancer Institute, Pennsylvania State University, Hershey, PA, 17033, USA.
Monika JoshiPenn State Cancer Institute, Pennsylvania State University, Hershey, PA, 17033, USA.
Stuthi PerimbetiPenn State Cancer Institute, Pennsylvania State University, Hershey, PA, 17033, USA.

Funding

Early clinial trials for Angelica herbal supplements for prostate cancer interceptionR01CA260901 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI JOSHI, MONIKA, LU, JUNXUAN · 2022 to 2025
$2.9M
Mechanisms of prostate cancer prevention by Korean AngelicaR01AT007395 · NCCIH · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI LU, JUNXUAN · 2012 to 2016
$2.2M
NCCIH NIH HHS R01 AT007395NCI NIH HHS R01 CA260901NCI NIH HHS R01CA260901
6 · The paper itself

Abstract

Angelica gigas Nakai (AGN) root is a medicinal herbal widely used in traditional medicine in Korea. AGN root ethanolic extracts have been marketed as dietary supplements in the United States for memory health and pain management. We have recently reviewed the pharmacokinetics (PK) and first-pass hepatic metabolism of ingested AGN supplements in humans for the signature pyranocoumarins decursin (D, C

Indexed as

AngelicaPhytochemicalsPlant ExtractsAnimalsBenzopyransButyratesHumansMedicine, Korean TraditionalPlant RootsBenzopyransButyratesdecursinPhytochemicalsPlant Extractsdecursindecursinoldecursinol angelatenodakeninROCK1/2

Identifiers

PMID39779619
PMCPMC11785709

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.