ArticleEuropean journal of medical research2025
The association between estimated pulse wave velocity and cardio-cerebrovascular disease risk: a cohort study.
Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of estimated pulse wave velocity with cardiovascular disease outcomes and all-cause death-a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Wearable ultrasound: a review of core technologies and clinical applications in cardiovascular monitoring.Microsystems & nanoengineering · 2026Review
- Development of an Oral Health Index and Its Association with Oral Health-Related Quality of Life and Cardiovascular Risks: A Cross-Sectional Study.International journal of environmental research and public health · 2026Observational
- Estimated pulse wave velocity and progression to advanced cardiovascular-kidney-metabolic syndrome: a population-based longitudinal study with supportive external cross-sectional evidence.Frontiers in cardiovascular medicine · 2026Article
- Ultrasound in cardiovascular care: a perspective on preventive, diagnostic, and monitoring applications.Frontiers in cardiovascular medicine · 2026Article
- Predicting 1-Year Renal Outcomes in Patients with Diabetic Kidney Disease in CKD Stages 3 to 4: A Multimodal Machine Learning Approach Fusing Clinical Composites and Pathology Images.Research (Washington, D.C.) · 2026Article
- Integrating Vascular Aging and Genetic Risk: The Combined Impact of Estimated Pulse Wave Velocity and Genetic Predisposition on Coronary Artery Disease.Journal of the American Heart Association · 2025Article
- Triglyceride-glucose index combined with estimated pulse wave velocity improves stroke risk stratification in the CHARLS cohort.Scientific reports · 2025Article
- Skin-Inspired Healthcare Electronics.Biomimetics (Basel, Switzerland) · 2025Review
- Temporal and joint associations of hypertension and estimated pulse wave velocity with incident cardiovascular diseases: a population-based cohort study.European journal of medical research · 2025Article
- ePWV as a scalable risk factor for large-scale glaucoma screening: evidence from a national Chinese cohort.Frontiers in cell and developmental biology · 2025Article
- Estimated pulse wave velocity as a potential predictor of albuminuria in hypertension.Frontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundVarious measures of arterial stiffness have been linked to the risk of cardiovascular disease. However, the relationship between the estimated pulse wave velocity (ePWV), a novel indicator of arterial stiffness, and cardio-cerebrovascular disease risk remains unclear. This study investigated the relationship between the ePWV and the risk of cardio-cerebrovascular diseases.
methodsA total of 17,708 participants aged 45 years and older enrolled in the China Health and Retirement Longitudinal Study (CHARLS), conducted between 2011 and 2012, and participants with a 7-year follow-up were included. Ultimately, 8242 respondents were included in the study. The ePWV was calculated using age and mean blood pressure. Cardio-cerebrovascular diseases, including myocardial infarction, cerebral infarction, and intracerebral haemorrhage, were categorised as cardiovascular and cerebrovascular diseases. Clinical and demographic characteristics were collected. A Cox proportional hazards model was used to explore the relationship between ePWV and the risk of cardiovascular disease.
resultsDuring the 7-year follow-up, 21.7% of the participants (1791/8242) developed cardio-cerebrovascular diseases. After adjusting for potential confounding factors, the ePWV was positively associated with the risk of cardio-cerebrovascular disease (adjusted hazard ratio: 1.16, 95% CI 1.11-1.22, P < 0.001). The ePWV was divided into quartiles, and regression analysis was performed. Participants in the highest ePWV quartile had a 128% higher risk of cardio-cerebrovascular disease than those in the lowest quartile. The subgroup analysis showed that the positive association between the ePWV and the risk of cardio-cerebrovascular disease remained consistent among middle-aged and older adults across different Chinese communities.
conclusionsIn middle-aged and older Chinese adults, the ePWV was significantly and positively associated with the risk of cardio-cerebrovascular disease, making it a reliable and innovative predictor of these conditions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.