Evidence map›Paper›PMID 39780282›Full record

ArticleJournal of eating disorders2025

Clinical characteristics of hospitalized male adolescents and young adults with avoidant/restrictive food intake disorder (ARFID).

Jason M Nagata, Anita V Chaphekar, Patrick Low, Ruben Vargas, Kyle T Ganson, Anthony Nguyen, Sara M Buckelew, Andrea K Garber, Amanda E Downey

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of eating disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jason M NagataDepartment of Pediatrics, University of California, San Francisco, San Francisco, CA, USA. Jason.Nagata@ucsf.edu.
Anita V ChaphekarDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Patrick LowDepartment of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
Ruben VargasDepartment of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
Kyle T GansonFactor-Inwentash Faculty of Social Work, University of Toronto, Toronto, ON, Canada.
Anthony NguyenDepartment of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
Sara M BuckelewDepartment of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
Andrea K GarberDepartment of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
Amanda E DowneyDepartment of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.

Funding

Institutional Career Development Core SupplementKL2TR001870 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SARKAR, URMIMALA · 2016 to 2025
$19.7M
Multi-center Randomized Controlled Trial of Refeeding in Anorexia NervosaR01HD082166 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GARBER, ANDREA K · 2015 to 2025
$5.7M
Investigating relationships between problematic social media use and binge-eating disorder to inform precision guidance for adolescentsR01MH135492 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAGATA, JASON M · 2023 to 2024
$1.0M
Informing national guidelines on adolescent and young adult physical activity and sedentary behavior to prevent cardiovascular diseaseK08HL159350 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAGATA, JASON M · 2021 to 2025
$869k
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD082166NCATS NIH HHS KL2 TR001870NCATS NIH HHS KL2TR001870NHLBI NIH HHS K08 HL159350NHLBI NIH HHS K08HL159350NICHD NIH HHS R01 HD082166NIMH NIH HHS R01 MH135492NIMH NIH HHS R01MH135492
6 · The paper itself

Abstract

backgroundAvoidant/restrictive food intake disorder (ARFID) may result in significant medical sequelae. Compared to youth with eating disorders like anorexia nervosa (AN), youth with ARFID tend to be younger and are more likely to be male. We aim to describe sex differences in clinical characteristics of youth hospitalized for medical complications of ARFID and compare their characteristics with youth hospitalized for anorexia nervosa.

methodsThis is a retrospective review of electronic medical records for youth with ARFID (N = 36; 13 male and 23 female) and AN (N = 355; 40 male and 315 female), including restricting and binge-eating/purging subtypes, aged 9-25 admitted to the inpatient UCSF Eating Disorders Program (2012-2020).

resultsA greater proportion of youth with ARFID were male compared to youth with AN (36.1% vs. 11.2%). Male youth with ARFID (mean age 15.5 ± 2.8) had lower heart rate nadir (49.2 vs. 57.6 beats per minute, p = .019) and lower total cholesterol (129.8 vs. 159.3 mg/dL, p = .008), but higher hemoglobin (13.9 vs. 13.0 g/dL, p = .015) and prescribed calories at discharge (3323 vs. 2817 kcal, p = .001) compared to females with ARFID. Males with AN, who on average had higher admission BMI than males with ARFID (17.3 vs. 15.5 kg/m

conclusionsARFID in males is associated with lower heart rate nadirs than in females with ARFID. Clinicians should be aware of unique medical complications in youth with ARFID compared to youth with AN.

Indexed as

Anorexia nervosaARFIDFeeding and eating disordersFemaleMaleRefeeding

Identifiers

PMID39780282
PMCPMC11716252

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.