Evidence map›Paper›PMID 39780331›Full record

SynthesisOrthopaedic surgery2025

Comparison of Therapeutic Effects of Different Rehabilitation Methods on Patients Undergoing Total Knee Arthroplasty: A Network Meta-Analysis of Randomized Controlled Trials.

Zhaokai Jin, Yi Tang, Hua Huang, Lei Chen, Zhongyi Zhang, Tianyou Ma, Zhengming Wang, Hai Su, Haojing Zhou, Shuaijie Lv and 1 more

Abstract readComparative StudyNetwork Meta-AnalysisSystematic Review
In one paragraph

Synthesis in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhaokai JinThe First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.ORCID https://orcid.org/0009-0006-7213-1247
Yi TangThe First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Hua HuangThe First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Lei ChenThe First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.ORCID https://orcid.org/0009-0009-4663-6550
Zhongyi ZhangThe First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Tianyou MaThe First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Zhengming WangShangai Academy of Traditional Chinese Medicine, Institute of Traumatology & Orthopedics, Shanghai, China.
Hai SuThe First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.ORCID https://orcid.org/0009-0001-0719-4683
Haojing ZhouThe First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.ORCID https://orcid.org/0009-0003-2505-745X
Shuaijie LvThe First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
Peijian TongThe First Affiliated Hospital of Zhejiang, Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.

Funding

National Natural Science Foundation of China 82274547
6 · The paper itself

Abstract

objectiveThe rehabilitation methods after total knee arthroplasty (TKA) can affect the recovery of complications and joint function, and the selection and comparison of rehabilitation methods after TKA still need further research.

methodsA comprehensive search of five databases and two clinical trial registration platforms was conducted from inception through March 31, 2024, and conducted to identify eligible randomized controlled trials (RCTs). We extracted the required data according to the Cochrane Handbook for Systematic Reviews of Interventions. Finally, 32 trials involving 2292 patients were included, the mean age of the enrolled patients was ~69.10 years, the sex ratio of males was (31.6%), and the longest follow-up time was 2 years. And we have summarized nine rehabilitation intervention measures: conventional physical therapy (CPT), cryotherapy, thermal therapy (TT), acupuncture, hydrotherapy, neuromuscular training (NT), electrotherapy, continuous passive motion (CPM), continuous active motion (CAM). And use the range of motion (ROM), visual analog scale (VAS), Western Ontario and McMaster Universities osteoarthritis index (WOMAC) as the outcome measure to evaluate the effectiveness of various interventions. A Bayesian network meta-analysis (NMA) was carried out for calculating standardized mean difference (SMD) and the surface under cumulative ranking curve (SUCRA) of improvement of knee joint function after TKA by different rehabilitation methods.

resultAfter treatment, the ROM results showed that cryotherapy, electrotherapy, and NT had better therapeutic effects. Among them, cryotherapy (WMD = 10.3, 95% CI 1.63-18.2) had a significant therapeutic effect. In terms of VAS, NT and TT showed good therapeutic effects. Among them, NT had a more significant therapeutic effect, while CAM had less effect. After treatment, in terms of WOMAC, TT, hydrotherapy, cryotherapy, and NT had better therapeutic effects. TT had the best therapeutic effect, while Hydrotherapy and Cryotherapy also had certain advantages.

conclusionNT, TT, cryotherapy, hydrotherapy, and electrotherapy rehabilitation therapies have good therapeutic effects for TKA patients compared with other interventions. Among them, NT may be the best postoperative rehabilitation therapy.

Indexed as

Arthroplasty, Replacement, KneePhysical Therapy ModalitiesHumansRandomized Controlled Trials as Topiccryotherapynetwork meta‐analysisneuromuscular trainingrehabilitationTKA

Identifiers

PMID39780331
PMCPMC11787976

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.