Evidence mapPaperPMID 39780503Full record

ReviewAndrology2025

Introduction to androgenetics: terminology, approaches, and impactful studies across 60 years.

Arvand Akbari, Laura Kasak, Maris Laan

Abstract readHistorical ArticleReview
In one paragraph

Review in Andrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Arvand AkbariCenter for Embryonic Cell & Gene Therapy, Oregon Health & Science University, Portland, Oregon, USA.
Laura KasakChair of Human Genetics, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Maris LaanChair of Human Genetics, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.ORCID 0000-0002-8519-243X

Funding

Project IIIP50HD096723 · MAGEE-WOMEN'S RES INST AND FOUNDATION · 2025 to 2025
$1.6M
Genomics of spermatogenic impairmentR01HD078641 · OREGON HEALTH & SCIENCE UNIVERSITY · 2025 to 2025
$616k
Eesti Teadusagentuur PRG1021NICHD NIH HHS P50 HD096723NICHD NIH HHS R01 HD078641NIH HHS P50HD096723NIH HHS R01HD078641
6 · The paper itself

Abstract

Across six decades, androgenetics has consistently concentrated on discovering genetic causes and enhancing the molecular diagnostics of male infertility, disorders of sex development, and their broader implications on health, such as cancer and other comorbidities. Despite vast clinical knowledge, the training of andrologists often lacks fundamental basics in medical genetics. This work, as part of the Special Issue of Andrology "Genetics in Andrology", provides the core terminology in medical genetics and technological advancements in genomics, required to understand the ever-progressing research in the field. It also gives an overview of study designs and approaches that have frequently led to discoveries in androgenetics. The rapid progress in the methodological toolbox in human genetics is illustrated by numerous examples of impactful androgenetic studies over 60 years, and their clinical implications.

Indexed as

AndrologyGenetics, MedicalInfertility, MaleTerminology as TopicHistory, 21st CenturyHumansMaleandrogeneticsclinical implicationsgenotype‐phenotype correlationsgonadal developmentinfertilitymale reproductionmedical genetics terminologymolecular diagnostics

Identifiers

PMID39780503
PMCPMC12794392

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.