ArticleMolecular biology of the cell2025
Behind the scenes of cellular organization: Quantifying spatial phenotypes of puncta structures with statistical models including random fields.
Article in Molecular biology of the cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Visualisation of peroxisomes: a journey through seven decades.Histochemistry and cell biology · 2026Review
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5 authors.
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Abstract
The cellular interior is a spatially complex environment shaped by nontrivial stochastic and biophysical processes. Within this complexity, spatial organizational principles-also called spatial phenotypes-often emerge with functional implications. However, identifying and quantifying these phenotypes in the stochastic intracellular environment is challenging. To overcome this challenge for puncta, we discuss the use of inference of point-process models that link the density of points to other imaged structures and a random field that captures hidden processes. We apply these methods to simulated data and multiplexed immunofluorescence images of Vero E6 cells. Our analysis suggests that peroxisomes are likely to be found near the perinuclear region, overlapping with the endoplasmic reticulum, and located within a distance of 1
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