Evidence mapPaperPMID 39787184Full record

ArticlePLOS global public health2025

Enhancing engagement in HIV care among adolescents and young adults: A focus on phone-based navigation and relationship building to address barriers in HIV care.

Harriet Fridah Adhiambo, Chanda Mwamba, Jayne Lewis-Kulzer, Sarah Iguna, Gladys Moraa Ontuga, Dorothy Imbuka Mangale, Everlyne Nyandieka, James Nyanga, Isaya Opondo, Joseph Osoro and 8 more

Abstract read
In one paragraph

Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Harriet Fridah AdhiamboResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.ORCID https://orcid.org/0000-0002-5323-5474
Chanda MwambaCentre for Infectious Disease Research in Zambia, Lusaka, Zambia.ORCID https://orcid.org/0000-0002-7626-6273
Jayne Lewis-KulzerDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, California, United States of America.
Sarah IgunaResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Gladys Moraa OntugaResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Dorothy Imbuka MangaleDepartment of Medicine, Washington University in St. Louis, St. Louis, Missouri, United States of America.
Everlyne NyandiekaResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
James NyangaResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Isaya OpondoResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Joseph OsoroResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Lina MontoyaDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Edwin NyagesoaResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Norton SangResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Eliud AkamaResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Elizabeth BukusiResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.
Lisa AbuogiDepartment of Pediatrics, University of Colorado, Denver, Colorado, United States of America.
Elvin GengDepartment of Medicine, Washington University in St. Louis, St. Louis, Missouri, United States of America.
Zachary Arochi KwenaResearch Care Training Program, Centre for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.

Funding

What works, for whom? Applying novel precision medicine methods to people with mental illness in the justice system.R00MH133985 · UNIV OF NORTH CAROLINA CHAPEL HILL · 2025 to 2025
$480k
Achieving successful treatment outcomes among adolescents and pregnant/postpartum women living with HIV in KenyaK24AI175015 · UNIVERSITY OF COLORADO DENVER · 2025 to 2025
$190k
MENTORING MULTIDISCIPLINARY PATIENT-ORIENTED RESEARCH IN ENGAGEMENT IN HIV CAREK24AI134413 · WASHINGTON UNIVERSITY · 2025 to 2025
$141k
NIAID NIH HHS K24 AI134413NIAID NIH HHS K24 AI175015NIMH NIH HHS R00 MH133985
6 · The paper itself

Abstract

Structural, psychological, and clinical barriers to HIV care engagement among adolescents and young adults living with HIV (AYAH) persist globally despite gains in HIV epidemic control. Phone-based peer navigation may provide critical peer support, increase delivery flexibility, and require fewer resources. Prior studies show that phone-based navigation and automated text messaging interventions improve HIV care engagement, adherence, and retention among AYAH. However, little is known about AYAH experiences utilizing electronic phone-based peer navigation and automated text messaging (E-NAV). We assessed the experiences of AYAH receiving phone-based peer navigation to address barriers to HIV care engagement and viral suppression. We purposefully selected participants randomized to E-NAV within the Adapt for Adolescents in Kisumu, Kenya, and conducted 20 in-depth interviews. Interviews were conducted by a trained qualitative researcher between October and December 2021 and explored topics such as health-seeking and care experiences, E-NAV acceptability and benefits, and the client-navigator relationship. The interviews were audio-recorded and transcribed. We then applied inductive and deductive coding, followed by thematic analysis. Overall, participants found E-NAV acceptable in regard to content and frequency-particularly the opportunity to select a preferred time for calls/text messages, including evenings and weekends. They found the tone of navigator calls and messages friendly, supporting relationship building. Further, AYAH-navigator relationships were described as fraternal, client-focused, and confidential, which supported a personal connection and trust. Reported E-NAV benefits included adherence and appointment reminders, increased knowledge about HIV care, and strategies to address HIV stigma. Electronic navigation is a promising method for youth peer navigation because it optimizes reach (both in time and space) for youth that have severe constraints on both while preserving the ability to create a rapport and a relationship with patients.

Identifiers

PMID39787184
PMCPMC11717212

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.