Evidence map›Paper›PMID 39787210›Full record

ArticleScience (New York, N.Y.)2025

Parallel gene expansions drive rapid dietary adaptation in herbivorous woodrats.

Dylan M Klure, Robert Greenhalgh, Teri J Orr, Michael D Shapiro, M Denise Dearing

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Dietary-Driven Gene Expansion.Clinical pharmacology and therapeutics · 2026
    Review
  8. Article
  9. Article
  10. Large-scale surveys of woodrats (Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dylan M Klure *School of Biological Sciences, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0001-8676-3006
Robert Greenhalgh *School of Biological Sciences, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0003-2816-3154
Teri J OrrSchool of Biological Sciences, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0001-6247-5237
Michael D ShapiroSchool of Biological Sciences, University of Utah, Salt Lake City, UT, USA.
M Denise DearingSchool of Biological Sciences, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0001-7881-4934

Funding

University of Utah Genetics Training ProgramT32GM141848 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI GOLIC, KENT G, GRUNWALD, DAVID J. · 2021 to 2025
$2.9M
Developmental and genetic mechanisms of diversity and diseaseR35GM131787 · NIGMS · UNIVERSITY OF UTAH · PI SHAPIRO, MICHAEL DAVID · 2019 to 2023
$2.1M
NIGMS NIH HHS R35 GM131787NIGMS NIH HHS T32 GM141848
6 · The paper itself

Abstract

How mammalian herbivores evolve to feed on chemically defended plants remains poorly understood. In this study, we investigated the adaptation of two species of woodrats (

Indexed as

Adaptation, PhysiologicalFeeding BehaviorGene DosageGlucuronic AcidGlucuronidesHerbivoryLarreaSigmodontinaeAnimalsDietGene DuplicationMetabolic Networks and PathwaysGlucuronic AcidGlucuronides

Identifiers

PMID39787210
PMCPMC12172070

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.