ArticleThe journal of nutrition, health & aging2025
Postprandial inflammation across the aging spectrum.
Article in The journal of nutrition, health & aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- A single-center study on prosthesis selection strategy in aortic valve replacement for patients aged 50-65 years.Journal of thoracic disease · 2026Article
- Postprandial metabolic effects of milk and yoghurt in young and older adults.Genes & nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectivesPostprandial inflammation post-high-fat meals may be linked to cardiovascular disease (CVD). CVD incidence increases with age; however, whether older adults experience greater postprandial inflammation remains unclear. We examined whether analyzing age categorically versus continuously influenced relationships between age and postprandial inflammatory measures.
designCross-sectional.
settingLaboratory for Applied Nutrition and Exercise Science at Oklahoma State University (Stillwater, OK, USA).
participants56 apparently healthy adults ages 20-69 years. MEASUREMENTS: We measured interleukin (IL)-1β, IL-6, IL-8, IL-10, and tumor necrosis factor (TNF)-α at baseline, 2-, 4-, and 6 -hs post-high-fat meal (9 kcal/kg; 70% fat). Data were examined in the full sample with paired t-tests (baseline to peak), by pre-defined age groups (i.e., 18-35, 36-49, 50-59, 60-69) using ANCOVA, and continuously using linear regression.
resultsAcross the full sample, IL-1β, IL-6, and IL-8 increased after the high-fat meal (p's≤0.018). Cytokine differences post-high-fat meal by age category were generally not observed. However, age was positively associated with IL-6 incremental AUC when examined continuously (b = 0.029; p = 0.010).
conclusionThese data suggest increasing age is linked to a greater IL-6 response to a high-fat meal. Further, examining age continuously may have greater utility when studying aging and postprandial inflammation. REGISTRATION: N/A (secondary analysis).
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Registered trials
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