ArticleBrain and behavior2025
Bibliometric Analysis of Neuroinflammation and Postoperative Cognitive Dysfunction.
Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of transcutaneous electrical acupoint stimulation on recovery following gynecological laparoscopic surgery: a meta-analysis.BMC surgery · 2026Pooled it
- Targeting Mitochondria for Postoperative Cognitive Dysfunction: From Mechanisms to Therapeutics.Molecular neurobiology · 2026Review
- Meningeal lymphatic dysfunction mediates postoperative sleep deprivation-induced cognitive decline via impaired neuroinflammatory clearance.Journal of neuroinflammation · 2026Article
- The Mediation of Circulating Inflammatory Proteins in the Causal Pathway From Immune Cells to Delirium.Brain and behavior · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundThe occurrence and development of postoperative cognitive dysfunction (POCD) are closely linked to neuroinflammation. This bibliometric analysis aims to provide novel insights into the research trajectory, key research topics, and potential future development trends in the field of neuroinflammation-induced POCD.
methodsThe Web of Science Core Collection (WoSCC) database was searched to identify publications from 2012 to 2023 on neuroinflammation-induced POCD. Bibliometric analysis, involving both statistical and visual analyses, was conducted using CiteSpace, VOSviewer, and the R software.
resultsResearch on neuroinflammation-induced POCD has exhibited an increasing trend over the past 12 years. China had the highest number of publications, Nanjing Medical University had the most collaboration with other institutions, Zhiyi Zuo was the most published author, and the Journal of Neuroinflammation served as the primary publication in the field of neuroinflammation-induced POCD. The most frequent keyword was POCD. Keyword clustering analysis indicated that the predominant cluster is dexmedetomidine. Burst detection revealed that postoperative delirium (POD), perioperative neurocognitive disorders (PND), apoptosis, and epigenetic modifications were the future research trends.
conclusionsOur analysis identified the following key research areas associated with neuroinflammation-induced POCD: anesthesia, surgery, dexmedetomidine, NLRP3 inflammasome, and mechanism of neuroinflammation-induced POCD. The potential future research topics comprise POD, PND, apoptosis, and epigenetic modifications.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.