Evidence map›Paper›PMID 39789984›Full record

ReviewHistology and histopathology2025

The potential protective effects of curcumin on the diabetic ovary: Experimental and molecular approaches.

Kıymet Kübra Tufekci, Gamze Altun, Maulilio John Kipanyula, Süleyman Kaplan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Histology and histopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kıymet Kübra TufekciDepartment of Histology and Embryology, Faculty of Medicine, Kastamonu University, Kastamonu, Türkiye.
Gamze AltunDepartment of Histology and Embryology, Ondokuz Mayıs University, Samsun, Türkiye.
Maulilio John KipanyulaThe Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania.
Süleyman KaplanDepartment of Histology and Embryology, Ondokuz Mayıs University, Samsun, Türkiye. skaplan@omu.edu.tr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus (DM) causes numerous systemic diseases in animals and humans. This may also lead to reproductive problems among individuals of reproductive age. Detrimental effects such as apoptosis in ovarian granulosa cells, degradation of communication proteins, decreased oocyte quality, delayed meiotic maturation, and atrophy are among the increasing evidence that chronic hyperglycemia causes reproductive problems. Numerous studies have reported that the antidiabetic properties of the antioxidant curcumin may be due to its inhibition of oxidative stress, inflammation, and insulin resistance. There are also data indicating that curcumin reduces the risk of DM and its associated symptoms. This review discusses the protective or curative properties of curcumin in the treatment of DM-related problems in the ovary and seeks to elucidate potential underlying mechanisms. While the use of curcumin as a supportive/therapeutic agent has been introduced for the reduction of reproductive problems that may be caused by uncontrolled DM, more studies on this subject are needed.

Indexed as

AntioxidantsCurcuminDiabetes MellitusHypoglycemic AgentsOvaryAnimalsFemaleHumansOxidative StressAntioxidantsCurcuminHypoglycemic Agents

Identifiers

PMID39789984

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.