Evidence mapPaperPMID 39790861Full record

ArticleAlzheimer's & dementia (New York, N. Y.)

Evaluation of efficiency and effectiveness of different recruitment strategies for the FINGER-NL multidomain lifestyle intervention trial via the Dutch Brain Research Registry.

Lisa Waterink, Sietske A M Sikkes, Lion M Soons, Sonja Beers, Yvonne Meijer-Krommenhoek, Ondine van de Rest, Smidt Nynke, Joukje M Oosterman, Erik Scherder, Kay Deckers and 6 more

Erratum issuedAbstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Modernizing diagnosis of Alzheimer's disease: A review of global trends and Asia-specific perspectives.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Lisa WaterinkAlzheimer Center Amsterdam Neurology Vrije Universiteit Amsterdam, Amsterdam UMC VUmc Amsterdam The Netherlands.ORCID https://orcid.org/0009-0002-5469-4098
Sietske A M SikkesAlzheimer Center Amsterdam Neurology Vrije Universiteit Amsterdam, Amsterdam UMC VUmc Amsterdam The Netherlands.
Lion M SoonsAlzheimer Centrum Limburg Department of Psychiatry and Neuropsychology School for Mental Health and Neuroscience (MHeNs) Maastricht University Maastricht The Netherlands.
Sonja BeersDivision of Human Nutrition and Health Wageningen University & Research Wageningen The Netherlands.
Yvonne Meijer-KrommenhoekDepartment of Epidemiology University Medical Center Groningen (UMCG) University of Groningen (RUG) Groningen The Netherlands.
Ondine van de RestDivision of Human Nutrition and Health Wageningen University & Research Wageningen The Netherlands.
Smidt NynkeDepartment of Epidemiology University Medical Center Groningen (UMCG) University of Groningen (RUG) Groningen The Netherlands.
Joukje M OostermanDonders Institute for Brain Cognition and Behaviour Radboud University Nijmegen The Netherlands.
Erik ScherderFaculty of Behavioural and Movement Sciences Department of Clinical Neuro and Developmental Psychology Vrije Universiteit Amsterdam The Netherlands.
Kay DeckersAlzheimer Centrum Limburg Department of Psychiatry and Neuropsychology School for Mental Health and Neuroscience (MHeNs) Maastricht University Maastricht The Netherlands.
Yannick VermeirenDivision of Human Nutrition and Health Wageningen University & Research Wageningen The Netherlands.
Rianne A A de HeusDepartment of Geriatrics Department of Primary and Community Care Radboud University Medical Center Radboud University Medical Center Radboudumc Alzheimer Center Nijmegen The Netherlands.
Sebastian KöhlerAlzheimer Centrum Limburg Department of Psychiatry and Neuropsychology School for Mental Health and Neuroscience (MHeNs) Maastricht University Maastricht The Netherlands.
Wiesje M van der FlierAlzheimer Center Amsterdam Neurology Vrije Universiteit Amsterdam, Amsterdam UMC VUmc Amsterdam The Netherlands.
MOCIA consortium, FINGER‐NL consortium
Marissa D ZwanAlzheimer Center Amsterdam Neurology Vrije Universiteit Amsterdam, Amsterdam UMC VUmc Amsterdam The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRecruitment of participants for intervention studies is challenging. We evaluated the effectiveness and efficiency of a participant recruitment campaign through an online registry for the FINGER-NL study, a multi-domain lifestyle intervention trial targeting cognitively healthy individuals aged 60-79 with dementia prevention potential. Additionally, we explored which recruitment strategy successfully reached individuals from underrepresented groups in research.

methodsThe campaign entailed seven recruitment strategies referring to The Dutch Brain Research Registry (DBRR): (1) Facebook advertisements, (2) appearance on national television, (3) newspaper articles, (4) researcher outreach, (5) patient organizations, (6) search engines, and (7) other. For each strategy, we describe the number of individuals (a) registered, (b) potentially eligible, and (c) included in FINGER-NL. Subsequently, the efficiency, defined by the eligibility ratio (eligible/registered), and effectiveness, defined by the inclusion ratio (included/registered) were calculated. Associations between recruitment strategies and sociodemographic factors of underrepresented groups were tested with binomial logistic regressions.

resultsThe campaign resulted in 13,795 new DBRR registrants, of which DISCUSSION: A multipronged recruitment campaign via a national online recruitment registry is efficient and effective in recruiting and prescreening an adequate number of individuals aged 60-79 years with prevention potential for a multi-site intervention trial within a limited time frame of 15 months. Social media advertisements and television are preferred strategies to recruit individuals from underrepresented groups. Highlights: An online brain research registry recruited eligible participants successfully.Mass media recruitment strategies are efficient for reaching large numbers.Direct recruitment through researchers and patient organizations seems more effective.Online registries offer automated prescreening and alternatives for screen-failures.Tailored strategies are needed to reach underrepresented groups to improve diversity.

Indexed as

agingdementialifestylerecruitmentregistriestrial

Identifiers

PMID39790861
PMCPMC11712179

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.