Evidence map›Paper›PMID 39791903›Full record

ArticleJournal of virology2025

Epithelial-to-mesenchymal transition and live cell extrusion contribute to measles virus release from human airway epithelia.

Camilla E Hippee, Lorellin A Durnell, Justin W Kaufman, Eileen Murray, Brajesh K Singh, Patrick L Sinn

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Camilla E HippeeMicrobiology and Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.
Lorellin A DurnellMicrobiology and Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.
Justin W KaufmanStead Family Department of Pediatrics, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.
Eileen MurrayStead Family Department of Pediatrics, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.
Brajesh K SinghStead Family Department of Pediatrics, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-5311-543X
Patrick L SinnMicrobiology and Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA.ORCID 0000-0002-9746-966X

Funding

Spread and Release of Measles in the AirwaysR01AI132402 · NIAID · UNIVERSITY OF IOWA · PI SINN, PATRICK L · 2018 to 2022
$3.0M
Training in Molecular Virology, Viral Pathogenesis and Viral VectorsT32AI007533 · NIAID · UNIVERSITY OF IOWA · PI Stanley Perlman · 1998 to 2026
$2.5M
Foundation for the National Institutes of Health (FNIH) T32 AL-007533NIAID NIH HHS R01 AI132402NIAID NIH HHS T32 AI007533
6 · The paper itself

Abstract

Measles virus (MeV) is a highly contagious respiratory virus transmitted via aerosols. To understand how MeV exits the airways of an infected host, we use unpassaged primary cultures of human airway epithelial cells (HAE). MeV typically remains cell-associated in HAE and forms foci of infection, termed infectious centers, by directly spreading cell-to-cell. We previously described the phenomenon in which infectious centers detach

Indexed as

Epithelial CellsEpithelial-Mesenchymal TransitionMeaslesMeasles virusRespiratory MucosaVirus ReleaseCells, CulturedHumanscell detachmentprimary human cellssphingosine kinaseTGF-βviral infectionwound healing

Identifiers

PMID39791903
PMCPMC11852777

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.