Evidence mapPaperPMID 39792169Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

The clinical impact of chronopharmacology on current medicine.

Mert Kaşkal, Mustafa Sevim, Gökay Ülker, Caner Keleş, Berna Terzioğlu Bebitoğlu

Abstract readReview
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Chrononutrition: Potential, Challenges, and Application in Managing Obesity.International journal of molecular sciences · 2025
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mert KaşkalDepartment of Pharmacology, School of Medicine, Marmara University, Istanbul, Turkey. mertkaskal@hotmail.com.
Mustafa SevimDepartment of Physiology, School of Medicine, Marmara University, Istanbul, Turkey.
Gökay ÜlkerDepartment of Pharmacology, School of Medicine, Marmara University, Istanbul, Turkey.
Caner KeleşDepartment of Pharmacology, School of Medicine, Marmara University, Istanbul, Turkey.
Berna Terzioğlu BebitoğluDepartment of Pharmacology, School of Medicine, Marmara University, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the goals of clinical pharmacology is to optimize patient treatment by adopting new treatment strategies which will increase the efficacy of the treatment and decrease the adverse effects of the drugs. In the literature, it has shown that the effectiveness and toxicity of medications can vary significantly based on when they are administered, making timing a crucial factor in treatment plans. Chronopharmacology a relatively new branch of clinical pharmacology focuses on adjusting drug administration times to enhance patient outcomes. Chronopharmacology is largely influenced by an individual's circadian rhythm which refers to periodic changes in biological processes depending on the time of the day. The chronopharmacology influences clinical practice, and the accumulating knowledge in this field will likely lead healthcare providers to adopt new strategies for drug treatment regimens. This review aims to summarize the impact of chronopharmacology particularly on current clinical practices and highlight the latest findings related to chronophysiological mechanisms.

Indexed as

ChronopharmacokineticsCircadian RhythmDrug ChronotherapyPharmacology, ClinicalAnimalsDrug Administration ScheduleHumansChronopharmacodynamicsChronopharmacokineticsChronophysiologyCircadian rhythmPersonalized medicine

Identifiers

PMID39792169
PMCPMC12125046

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.