Evidence map›Paper›PMID 39792288›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

The ecdysone-induced bZIP transcription factor MafB establishes a positive feedback loop to enhance vitellogenesis and reproduction in the

Jia-Lin Wang, Zi-Qian Zhong, Ya-Zhou He, Jun-Hua Tian, Yu-Feng Wang, Alexander S Raikhel

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Transcriptome Analysis of the Larch Bud Gall Midge,International journal of molecular sciences · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jia-Lin Wang *Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan 430079, China.
Zi-Qian Zhong *Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan 430079, China.
Ya-Zhou HeDepartment of Entomology, University of California, Riverside, CA 92521.ORCID 0000-0001-6550-868X
Jun-Hua TianWuhan Center for Disease Control and Prevention, Wuhan 430022, China.
Yu-Feng WangHubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan 430079, China.
Alexander S RaikhelDepartment of Entomology, University of California, Riverside, CA 92521.

Funding

China Scholarship Council (CSC) 201506775010Fundumental Research Funds for the Centrla Universities China CCNU22LJ003HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01 A1036959
6 · The paper itself

Abstract

Female mosquitoes require a vertebrate blood meal to activate reproduction, transmitting numerous devastating human diseases. Vitellogenesis is a central event of female reproduction that involves the massive production of vitellogenin (Vg) in the fat body and the maturation of ovaries. This process is controlled by the steroid hormone 20-hydroxyecdysone (20E); however, its molecular regulatory basis remains not completely understood. We found that the expression of

Indexed as

AedesReproductionVitellogenesisAnimalsBasic-Leucine Zipper Transcription FactorsEcdysoneEcdysteroneFemaleInsect ProteinsPromoter Regions, GeneticReceptors, SteroidBasic-Leucine Zipper Transcription FactorsEcdysoneecdysone receptorEcdysteroneInsect ProteinsReceptors, Steroid20-hydroxyecdysoneCncCMafBshadevitellogenin

Identifiers

PMID39792288
PMCPMC11745349

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.