ArticleScience immunology2025
Multiomics dissection of human RAG deficiency reveals distinctive patterns of immune dysregulation but a common inflammatory signature.
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Article in Science immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14citing papers in PubMed
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Who cites it
14 citing papers in PubMed.
- RAG1 lentiviral gene therapy restores T-cell development of RAG1-SCID patient cells in artificial thymic organoids.Blood advances · 2025Trial
- ABO: A 3D stroma-supported culture platform enabling full human B-lymphopoiesis for disease modeling and gene therapy development.Cell reports. Medicine · 2026Article
- C5 inhibition restores B cell homeostasis and humoral immunity in CHAPLE disease patients.Journal of human immunity · 2026Article
- Human CD21Journal of human immunity · 2026Review
- Allogeneic hematopoietic cell transplantation for partial RAG deficiency in children and adults: Excellent outcomes with a reduced-intensity posttransplantation cyclophosphamide-based approach.The Journal of allergy and clinical immunology · 2026Article
- Dominant-negative PSMB10 disrupts immunoproteasome assembly and leads to transient T lymphopenia.Journal of human immunity · 2026Article
- Immune-related actinopathies at the cross-road of immunodeficiency, autoimmunity and autoinflammation.Nature reviews. Immunology · 2026Review
- Digital immune twins and ai-integrated multi-omic biomarkers: Redefining personalized immunotherapy in non-small cell lung cancer.Iranian journal of basic medical sciences · 2026Review
- Phantom of the immunologic opera: Unmasking the role of innate lymphoid cells (ILC) in inborn errors of immunity (IEI).Journal of human immunity · 2025Review
- Inflammatory arthritis immune related adverse events represent a unique autoimmune disease entity primarily driven by T cells, but likely not autoantibodies.medRxiv : the preprint server for health sciences · 2025Article
- Immunopathological and microbial signatures of inflammatory bowel disease in partial RAG deficiency.The Journal of experimental medicine · 2025Article
- Factors associated with and kinetics of anti-IFN-α autoantibodies inThe journal of allergy and clinical immunology. Global · 2025Article
- Human immunity.Journal of human immunity · 2025Article
- Mapping the landscape of autoimmunity and autoinflammation in inborn errors of immunity: broad distribution with distinct clustering patterns.Frontiers in immunology · 2025Article
Corrections and comments
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Authors and funding
125 authors.
Marita BosticardoLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-1771-4523
Kerry DobbsLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-3432-3137
Ottavia M DelmonteLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-4772-0799
Andrew J MartinsMultiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0002-1832-1924
Francesca PalaLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-4537-9061
Tomoki KawaiLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-0375-9752
Heather KenneyLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Gloria MagroLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-1646-227X
Lindsey B RosenLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-5894-3878
Yasuhiro YamazakiLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-0327-1618
Hsin-Hui YuLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-2611-5175
Enrica CalzoniLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-4080-2350
Yu Nee LeePediatric Department A and the Immunology Service, Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, 52621 Tel HaShomer, Israel.ORCID 0000-0001-8648-5253
Can LiuMultiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0002-8411-3891
Jennifer StoddardImmunology Service, Department of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, MD, USA.
Julie NiemelaImmunology Service, Department of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, MD, USA.ORCID 0000-0003-4197-3792
Danielle FinkNeutrophil Monitoring Laboratory, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Riccardo CastagnoliLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-0029-9383
Meredith RambaPrecision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.ORCID 0000-0002-4770-9389
Aristine ChengLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-1182-7375
Deanna RileyLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-2440-4195
Vasileios OikonomouLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Elana ShawLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-9265-8026
Brahim BelaidDepartment of Medical Immunology, Beni Messous University Hospital Center, Faculty of Pharmacy, University of Algiers, Algiers, Algeria.ORCID 0000-0001-7618-4051
Sevgi KelesDivision of Pediatric Allergy and Immunology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
Waleed Al-HerzDepartment of Pediatrics, College of Medicine, Kuwait University, Safat, Kuwait City, Kuwait.ORCID 0000-0003-4244-4489
Caterina CancriniDepartment of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.ORCID 0000-0001-8410-9617
Cristina CifaldiDepartment of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.ORCID 0000-0002-7170-7279
Safa BarisFaculty of Medicine, Division of Pediatric Allergy and Immunology, Marmara University, Istanbul, Turkey.ORCID 0000-0002-4730-9422
Svetlana SharapovaBelarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.ORCID 0000-0003-1390-2348
Catharina SchuetzDepartment of Paediatrics, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.ORCID 0000-0001-8731-8924
Andrew R GenneryTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0002-6218-1324
Alexandra F FreemanLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-7005-8345
Raz SomechPediatric Department A and the Immunology Service, Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, 52621 Tel HaShomer, Israel.
Sharon ChooDepartment of Allergy and Immunology, Royal Children's Hospital, Melbourne, VIC, Australia.
Silvia C GilianiAngelo Nocivelli Institute for Molecular Medicine, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.ORCID 0000-0001-8137-4642
Tayfun GüngörDivision of Hematology/Oncology/Immunology, Gene-Therapy, and Stem Cell Transplantation, University Children's Hospital Zürich, Zürich, Switzerland.ORCID 0000-0002-3261-1186
Daniel DrozdovDivision of Hematology/Oncology/Immunology, Gene-Therapy, and Stem Cell Transplantation, University Children's Hospital Zürich, Zürich, Switzerland.ORCID 0000-0002-3010-7525
Isabelle MeytsDepartment of Immunology and Microbiology, Inborn Errors of Immunity, KU Leuven, Leuven, Belgium.ORCID 0000-0003-1214-0302
Despina MoshousHôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France.ORCID 0000-0001-6719-3693
Benedicte NevenHôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France.
Roshini S AbrahamDepartment of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, OH, USA.ORCID 0000-0001-8109-8502
Aisha El-MarsafyDepartment of Pediatrics, Faculty of Medicine, Cairo University, Cairo, Egypt.
Maria KanariouDepartment of Immunology-Histocompatibility, Specialized & Referral Center for Primary Immunodeficiencies-Paediatric Immunology, "Aghia Sophia" Children's Hospital, Athens, Greece.ORCID 0000-0003-0923-2118
Alejandra KingDepartamento de Pediatría, Hospital Luis Calvo Mackenna, Santiago, Chile.
Francesco LicciardiImmuno-reumatologia, Pediatria Specialistica Universitaria, Ospedale Infantile Regina Margherita, Torino, Italy.
Mario E Cruz-MuñozFacultad de Medicina, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, Mexico.ORCID 0000-0001-6851-708X
Paolo PalmaDepartment of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.ORCID 0000-0002-8465-3265
Cecilia PoliFaculty of Medicine, Clínica Alemana Universidad del Desarrollo Roberto del Rio, Santiago, Chile.ORCID 0000-0001-6817-0573
Mehdi AdeliDepartment of Immunology, Sidra Medicine, Ar-Rayyan, Qatar.ORCID 0000-0002-3051-3080
Mattia AlgeriDepartment of Hematology/Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.ORCID 0000-0002-6673-2664
Fayhan J AlroqiKing Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.ORCID 0000-0001-5271-0002
Paul BastardPediatric Hematology-Immunology and Rheumatology Unit, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.ORCID 0000-0002-5926-8437
Jenna R E BergersonLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Claire BoothMolecular and Cellular Immunology, UCL Great Ormond Street Institute of Child Health, London, UK.ORCID 0000-0002-2626-5037
Ana BrettHospital Pediátrico, Unidade Local de Saúde de Coimbra, Coimbra, Portugal.ORCID 0000-0002-6762-3515
Siobhan O BurnsInstitute of Immunity and Transplantation, University College London, London, UK.ORCID 0000-0002-3356-9506
Manish J ButteDepartment of Pediatrics, Division of Immunology, Allergy, and Rheumatology, University of California, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-4490-5595
Nurcicek PademDivision of Pediatric Pulmonology, Allergy-Immunology and Sleep Medicine, Riley Hospital for Children/Indiana University, Indianapolis, IN, USA.ORCID 0000-0001-9558-0746
M de la MorenaDivision of Immunology, Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.
Ghassan DbaiboDepartment of Pediatrics and Adolescent Medicine, Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Suk See de RavinLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-9800-774X
Dimana DimitrovaExperimental Transplantation and Immunotherapy Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-4868-6852
Reda DjidjikDepartment of Medical Immunology, Beni Messous University Hospital Center, Faculty of Pharmacy, University of Algiers, Algiers, Algeria.ORCID 0000-0003-0820-692X
Mayra B DornaDivision of Allergy and Immunology, Department of Pediatrics, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.ORCID 0000-0002-0168-7807
Cullen M DutmerAllergy and Immunology Section, Children's Hospital Colorado and University of Colorado School of Medicine, Aurora, CO, USA.ORCID 0000-0001-9806-4739
Reem ElfekyDepartment of Clinical Immunology, Royal Free Hospital, London, UK.ORCID 0000-0001-9382-150X
Fabio FacchettiSection of Pathology, Department of Molecular and Translational Medicine, University of Brescia, Spedali Civili di Brescia, Brescia, Italy.ORCID 0000-0003-4975-2388
Ramsay L FuleihanDivision of Allergy & Immunology, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0002-8477-9239
Raif S GehaDivision of Immunology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0001-8262-9686
Luis I Gonzalez-GranadoPrimary Immunodeficiency Unit, Pediatrics, Hospital 12 Octubre, Madrid, Spain.ORCID 0000-0001-6917-8980
Liis HaljasmägiInstitute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.ORCID 0000-0001-7162-9808
Hanadys AleDivision of Immunology, Allergy and Rheumatology, Joe DiMaggio Children's Hospital, Memorial Healthcare System, Hollywood, FL, USA.
Anthony HaywardDivision of Infectious Diseases, Department of Pediatrics, Brown University and Rhode Island Hospital, Providence, RI, USA.ORCID 0000-0003-3123-2894
Anna M HifanovaDepartment of Pediatric Infectious Diseases and Pediatric Immunology, Shupyk National Healthcare University of Ukraine, Kiev, Ukraine.ORCID 0000-0002-2541-0327
Winnie IpMolecular and Cellular Immunology, UCL Great Ormond Street Institute of Child Health, London, UK.ORCID 0000-0002-1550-4856
Blanka KaplanDivision of Allergy, Asthma and Immunology, Cohen Children's Medical Center, Northwell Health, New Hyde Park, NY, USA.ORCID 0000-0002-7439-1409
Neena KapoorChildren's Hospital of Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-3352-9651
Elif Karakoc-AydinerFaculty of Medicine, Division of Pediatric Allergy and Immunology, Marmara University, Istanbul, Turkey.ORCID 0000-0003-4150-5200
Jaanika KärnerInstitute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.ORCID 0000-0002-3548-5023
Michael D KellerDivision of Allergy and Immunology, Children's National Hospital, Washington, DC, USA.ORCID 0000-0001-8323-3085
Blachy J Dávila SaldañaDivision of Allergy and Immunology, Children's National Hospital, Washington, DC, USA.ORCID 0000-0001-8281-3627
Ayça KiykimDivision of Pediatric Allergy and Immunology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.ORCID 0000-0001-5821-3963
Taco W KuijpersDepartment of Pediatric Immunology, Amsterdam UMC Locatie AMC, Amsterdam, Netherlands.ORCID 0000-0002-7421-3370
Elena E KuznetsovaHematology Department, Regional Clinical Hospital, Orenburg, Russia.
Elena A LatyshevaImmunopathology Department, NRC Institute of Immunology FMBA, Pigorov Russian National Research Medical University, Moscow, Russia.ORCID 0000-0002-1606-205X
Jennifer W LeidingDivision of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-7573-9390
Franco LocatelliDepartment of Hematology/Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.ORCID 0000-0002-7976-3654
Guisela Alva-LozadaAllergy and Immunology Division Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru.
Christine McCuskerDivision of Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC, Canada.ORCID 0000-0003-2150-9159
Fatih CelmeliImmunology and Allergy Diseases, Saglık Bilimleri University, Antalya Training and Research Hospital Pediatric, Antalya, Turkey.ORCID 0000-0002-2983-5058
Megan MorsheimerDivision of Allergy, Immunology and Transplantation, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Ahmet OzenFaculty of Medicine, Division of Pediatric Allergy and Immunology, Marmara University, Istanbul, Turkey.ORCID 0000-0002-9065-1901
Nima ParvanehInfectious Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-3397-9716
Srdjan PasicDepartment of Pediatric Immunology, Mother and Child Health Institute, Medical Faculty, University of Belgrade, Belgrade, Serbia.ORCID 0000-0001-7761-0024
Alessandro PlebaniUniversity of Brescia, Brescia, Italy.ORCID 0000-0002-2003-3307
Kahn PreeceDepartment of Immunology, John Hunter Children's Hospital, Newcastle, NSW, Australia.ORCID 0000-0002-7326-6585
Susan ProckopDana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.ORCID 0000-0003-4175-5728
Inga S SakovichBelarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus.
Elena E StarkovaClinical Department, Regional Clinical Hospital No. 2, Orenburg, Russia.
Troy TorgersonAllen Institute for Immunology, Seattle, WA, USA.ORCID 0000-0003-3489-5036
James VerbskyDivision of Rheumatology, Department of Pediatrics, Medical College of Wisconsin and Children's Wisconsin, Milwaukee, WI, USA.ORCID 0000-0001-6682-1002
Jolan E WalterDivision of Pediatric Allergy/Immunology, University of South Florida at Johns Hopkins All Children's Hospital, St. Petersburg, FL, USA.ORCID 0000-0002-6192-0703
Brant WardDivision of Rheumatology, Allergy and Immunology, Virginia Commonwealth University, Richmond, VA, USA.ORCID 0009-0002-6035-9667
Elizabeth L WisnerDivision of Allergy Immunology, Department of Pediatrics, Louisiana State University Health Sciences Center New Orleans, New Orleans, LA, USA.
Deborah DraperLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0009-0001-9790-9645
Katherine Myint-HpuLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Pooi M TruongLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0009-0002-2825-7097
Michail S LionakisLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-4994-9500
Morgan B SimilukDivision of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-0403-2689
Centralized Sequencing Program Group§§
Magdalena A WalkiewiczDivision of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Amy KlionLaboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0002-4986-5326
Steven M HollandLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-3207-5464
Cihan OguzIntegrated Data Sciences Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-2860-3546
Dusan BogunovicCenter for Genetic Errors of Immunity, Columbia University Medical Center, New York City, NY, USA.
Kai KisandInstitute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.ORCID 0000-0002-5426-4648
Helen C SuLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-5582-9110
John S TsangMultiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0003-3186-3047
Douglas KuhnsNeutrophil Monitoring Laboratory, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.ORCID 0000-0002-9971-0760
Anna VillaMilan Unit, Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Milan, Italy.ORCID 0000-0003-4428-9013
Sergio D RosenzweigImmunology Service, Department of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, MD, USA.ORCID 0000-0002-5550-9678
Stefania PittalugaLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-7688-1439
Luigi D NotarangeloLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-8335-0262
Centralized Sequencing Program Group
Funding
Defining New Human Immunodeficiency and Immunodysregulation DisordersZIAAI001059 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SU, HELEN CHUN-HUI · 2009 to 2025
$20.5MCharacterization of the cellular and molecular bases of inborn errors of immunityZIAAI001222 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NOTARANGELO, LUIGI · 2017 to 2025
$15.2MType I Interferon Dysregulation in Down SyndromeR01AI150300 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BOGUNOVIC, DUSAN · 2019 to 2021
$3.8MInborn Errors of Immunity Leading to Autoinflammatory SyndromesR01AI148963 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BOGUNOVIC, DUSAN · 2020 to 2024
$2.5MMechanisms driving extrafollicular polyreactive B cell lineages in partial RAG deficiencyR01AI153830 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI WALTER, JOLAN ESZTER · 2021 to 2025
$2.2MIntramural NIH HHS ZIA AI001059Intramural NIH HHS ZIA AI001222NIAID NIH HHS R01 AI148963NIAID NIH HHS R01 AI150300NIAID NIH HHS R01 AI153830
Abstract
Human recombination-activating gene (RAG) deficiency can manifest with distinct clinical and immunological phenotypes. By applying a multiomics approach to a large group of
Indexed as
InflammationB-LymphocytesChild, PreschoolDNA-Binding ProteinsFemaleHomeodomain ProteinsHumansMaleMultiomicsMutationNuclear ProteinsPhenotypeDNA-Binding ProteinsHomeodomain ProteinsNuclear ProteinsRAG-1 proteinRAG2 protein, human
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