Evidence map›Paper›PMID 39794284›Full record

GuidelineNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2025

Dent disease: clinical practice recommendations.

Arend Bökenkamp, Gema Ariceta, Detlef Böckenhauer, Olivier Devuyst, Francesco Emma, David van Bennekom, Elena Levtchenko, John Sayer, Aude Servais, Rosa Vargas and 2 more

Abstract readPractice Guideline
In one paragraph

Guideline in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Database ofKidney international reports · 2026
    Article
  8. Review
  9. Review
  10. The kidney in genetic metabolic disorders.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2026
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Arend BökenkampDepartment of Pediatric Nephrology, Emma Children's Hospital, Amsterdam University Medical Center, Amsterdam, The Netherlands.ORCID 0000-0002-3492-2252
Gema AricetaPediatric Nephrology, Hospital Vall d' Hebron, Autonomous University of Barcelona, Barcelona, Spain.
Detlef BöckenhauerPediatric Nephrology, University Hospitals Leuven and Department of Cellular and Molecular Medicine, KUL, Leuven, Belgium.ORCID 0000-0001-5878-941X
Olivier DevuystInstitute of Physiology, University of Zurich, Zurich, Switzerland; UCLouvain Medical School, Brussels, Belgium.
Francesco EmmaDivision of Nephrology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.ORCID 0000-0002-0383-3468
David van BennekomEuropean Patient Advocate Group, ERKNet.
Elena LevtchenkoDepartment of Pediatric Nephrology, Emma Children's Hospital, Amsterdam University Medical Center, Amsterdam, The Netherlands.
John SayerTranslational and Clinical Research Institute, Newcastle University, Newcastle, UK.
Aude ServaisNephrology and Transplantation Department, Inherited Kidney Diseases Reference Center, Necker-Enfants Malades University Hospital, Assistance Publique Hôpitaux de Paris, Inserm U1163, Imagine Institute, Université de Paris, Paris, France.
Rosa VargasDepartment of Genetics, European Hospital Georges Pompidou, Paris, France.ORCID 0000-0002-4169-0680
Marcin ZaniewDepartment of Pediatrics, University of Zielona Góra, Zielona Góra, Poland.
Larisa PrikhodinaVeltishev Research Clinical Institute for Pediatrics & Pediatric Surgery, Pirogov Russian National Research Medical University, Moscow, Russia.ORCID 0000-0002-0702-4932

Funding

ERKNet 2021-2027
6 · The paper itself

Abstract

Dent disease is a rare X-linked tubulopathy that is characterized by low-molecular-weight proteinuria associated with hypercalciuria, which may lead to nephrolithiasis, nephrocalcinosis, and kidney failure between the third and fifth decades of life in 30%-80% of affected males. The disease is most often associated with various manifestations of proximal tubular dysfunction. Affected individuals may present nephrotic-range proteinuria which may be misinterpreted and cause diagnostic delay. Due to its rarity, there is limited evidence to guide diagnosis and management. These clinical practice recommendations summarize the current knowledge on Dent disease and provide guidance for diagnosis and management. The recommendations are based on a systematic search of the literature and were endorsed by a Delphi procedure among stakeholders in the field as well as the respective ERA and ESPN working groups.

Indexed as

Dent DiseaseHumansSystematic Reviews as Topicguidelinesnephrolithiasisproteinuriaproximal tubulesystematic review

Identifiers

PMID39794284
PMCPMC12209860

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.