Evidence map›Paper›PMID 39794424›Full record

ArticleScientific reports2025

The total extract of Abelmoschus manihot (L.) medic flowers (TEA) mediated Nrf2-TFAM signalling to regulate mitochondrial antioxidant mechanism.

Ying Song, Xinyi Zhu, Beibei Wang, Qisong Li, Biwei Song

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ying Song *Department of Pharmacology, Zhejiang University of Technology, 18 Chao-Wang Road, Hangzhou, 310014, Zhejiang, People's Republic of China. songying@zjut.edu.cn.
Xinyi Zhu *Department of Pharmacy, Huzhou Maternity & Child Health Care Hospital, Huzhou, 313000, Zhejiang, People's Republic of China.
Beibei WangDepartment of Pharmacology, Zhejiang University of Technology, 18 Chao-Wang Road, Hangzhou, 310014, Zhejiang, People's Republic of China.
Qisong LiDepartment of Pharmacology, Zhejiang University of Technology, 18 Chao-Wang Road, Hangzhou, 310014, Zhejiang, People's Republic of China.
Biwei SongDepartment of Pharmacology, Zhejiang University of Technology, 18 Chao-Wang Road, Hangzhou, 310014, Zhejiang, People's Republic of China.

Funding

National Natural Science Foundation of China 82174038Zhejiang Provincial Natural Science Foundation of China LD22H090002
6 · The paper itself

Abstract

Skin, as the first line of defence of the human body, is exposed to dangers such as overheating substances, ultraviolet rays, and environmental pollutants, and the incidence of skin diseases is increasing annually. Oxidative stress plays a dominant role in most skin diseases. Abelmoschus manihot (L.) medic flower (TEA) is a traditional Chinese medicine widely used to treat injuries to the skin such as water and fire scalds. It has been reported that TEA has excellent antioxidant effects. In this study, we aimed to explore the antioxidant and mitochondrial protection effects of TEA in H

Indexed as

AbelmoschusAntioxidantsDNA-Binding ProteinsFlowersMitochondriaMitochondrial ProteinsNF-E2-Related Factor 2Plant ExtractsSignal TransductionTranscription FactorsCell LineCell SurvivalHaCaT CellsHumansHydrogen PeroxideOxidative StressAntioxidantsDNA-Binding ProteinsHydrogen PeroxideMitochondrial ProteinsNFE2L2 protein, humanNF-E2-Related Factor 2Plant ExtractsReactive Oxygen SpeciesTranscription FactorsMitochondriaNrf2Oxidative stressTFAMThe total extract of Abelmoschus manihot (L.) Medic flowers (TEA)

Identifiers

PMID39794424
PMCPMC11723989

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.