ReviewMolecules (Basel, Switzerland)2024
Effects and Impact of Selenium on Human Health, A Review.
Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
63 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Role of Selenium During Gestation in the Development of Fetal Congenital Anomalies: A Systematic Review.Nutrients · 2026Pooled it
- Actual Data on Essential Trace Elements in Parkinson's Disease.Nutrients · 2025Pooled it
- Wound Healing Potential of Selenium and Nanoselenium.Biological trace element research · 2026Review
- The compound-independent calibration of alkyl organophosphorus flame retardants in rice using GC-ICP-MS.Analytical and bioanalytical chemistry · 2026Article
- Detection of preoperative serum trace elements in thyroid tumors.Gland surgery · 2026Article
- Selenite tolerance, reduction performance and biogenic selenium nanoparticle biosynthesis by Priestia aryabhattai YL286 isolated from the wheat phyllosphere.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Comparative Evaluation of the Effect of Foliar Nano-Se/Si Supply on the Yield and Nutritional Quality of Iceberg and Romaine Lettuce Grown in Hydroponics.Plants (Basel, Switzerland) · 2026Article
- Safety Assessment of Selenium-Biofortified Broccoli Seedlings: Insights from Repeated-Dose Toxicity and Genotoxicity Evaluation in Mice.Plants (Basel, Switzerland) · 2026Article
- Selenium-Loaded Calcium Phosphate with Long-Term and Curative Dosage Drug Release for Post-Surgical Osteosarcoma Management and Osteogenesis.International journal of molecular sciences · 2026Article
- Anti-Aging Potential of Biogenic Selenium Nanoparticles and Selenium/Polysaccharides Nanoconjugate Biosynthesized byAntioxidants (Basel, Switzerland) · 2026Article
- Selenoproteins: Minute yet vital players governing cellular fate.Genes & diseases · 2026Review
- Effect of a Se-enrichedFood chemistry: X · 2026Article
- Exploring the Potential of Bovine Whey Fermentation by Non-Selenized and SelenizedFoods (Basel, Switzerland) · 2026Article
- Maternal Anemia and Pediatric Neurodevelopment in Children from Mothers Exposed to Mixed Heavy Metals in Suriname.Journal of xenobiotics · 2026Article
- Transcriptomic Analysis of Selenium-Induced Antioxidant Responses in Diploid, Triploid, and Tetraploid Pacific Oysters (Foods (Basel, Switzerland) · 2026Article
- Synthesis and fungicidal activity of novel 1,1-diaryl-2-azolylethanols with a pyridine moiety.Molecular diversity · 2026Article
- Regulation Progresses of Selenium Improving Intestinal and Extra-Intestinal Tissues Health Through Regulating Gut Microbiota.Biology · 2026Review
- Vascular Aging and Atherosclerosis: The Modulatory Impact of Selenium-A Comprehensive Review.Cells · 2026Review
- Multimodal Exercise and Nutritional Interventions in Pediatric Cancer: Effects on Physical Function, Body Composition, and Metabolic Health-A Narrative Review.Children (Basel, Switzerland) · 2026Review
- Recent advances in exploring the composition and evolution of the prokaryotic selenoproteome.Applied and environmental microbiology · 2026Review
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Selenium (Se) is an essential trace element that is crucial for human health. As a key component of various enzymes and proteins, selenium primarily exerts its biological functions in the form of selenoproteins within the body. Currently, over 30 types of selenoproteins have been identified, with more than 20 of them containing selenocysteine residues. Among these, glutathione peroxidases (GPXs), thioredoxin reductases (TrxRs), and iodothyronine deiodinases (DIOs) have been widely studied. Selenium boasts numerous biological functions, including antioxidant properties, immune system enhancement, thyroid function regulation, anti-cancer effects, cardiovascular protection, reproductive capability improvement, and anti-inflammatory activity. Despite its critical importance to human health, the range between selenium's nutritional and toxic doses is very narrow. Insufficient daily selenium intake can lead to selenium deficiency, while excessive intake carries the risk of selenium toxicity. Therefore, selenium intake must be controlled within a relatively precise range. This article reviews the distribution and intake of selenium, as well as its absorption and metabolism mechanisms in the human body. It also explores the multiple biological functions and mechanisms of selenium in maintaining human health. The aim is to provide new insights and evidence for further elucidating the role of selenium and selenoproteins in health maintenance, as well as for future nutritional guidelines and public health policies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.