Evidence map›Paper›PMID 39795229›Full record

ArticleMolecules (Basel, Switzerland)2025

Exploring the Potential of Malvidin and Echiodinin as Probable Antileishmanial Agents Through In Silico Analysis and In Vitro Efficacy.

Luis Daniel Goyzueta-Mamani, Daniela Pagliara Lage, Haruna Luz Barazorda-Ccahuana, Margot Paco-Chipana, Mayron Antonio Candia-Puma, Gonzalo Davila-Del-Carpio, Alexsandro Sobreira Galdino, Ricardo Andrez Machado-de-Avila, Rodolfo Cordeiro Giunchetti, Edward L D'Antonio and 2 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Luis Daniel Goyzueta-MamaniComputational Biology and Chemistry Research Group, Vicerrectorado de Investigación, Universidad Católica de Santa María, Arequipa 04000, Peru.ORCID 0000-0003-0308-1160
Daniela Pagliara LagePrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.
Haruna Luz Barazorda-CcahuanaComputational Biology and Chemistry Research Group, Vicerrectorado de Investigación, Universidad Católica de Santa María, Arequipa 04000, Peru.ORCID 0000-0001-8791-0506
Margot Paco-ChipanaComputational Biology and Chemistry Research Group, Vicerrectorado de Investigación, Universidad Católica de Santa María, Arequipa 04000, Peru.
Mayron Antonio Candia-PumaComputational Biology and Chemistry Research Group, Vicerrectorado de Investigación, Universidad Católica de Santa María, Arequipa 04000, Peru.ORCID 0000-0002-6328-3840
Gonzalo Davila-Del-CarpioFacultad de Ciencias Farmacéuticas, Bioquímicas y Biotecnológicas, Universidad Católica de Santa María, Arequipa 04000, Peru.ORCID 0000-0001-7842-9286
Alexsandro Sobreira GaldinoLaboratório de Biotecnologia de Microrganismos, Universidade Federal São João Del-Rei, Divinópolis 35501-296, Brazil.ORCID 0000-0002-8890-3030
Ricardo Andrez Machado-de-AvilaPrograma de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma 88806-000, Brazil.ORCID 0000-0002-1303-0490
Rodolfo Cordeiro GiunchettiLaboratório de Biologia das Interações Celulares, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0003-4181-7546
Edward L D'AntonioDepartment of Natural Sciences, University of South Carolina Beaufort, 1 University Boulevard, Bluffton, SC 29909, USA.ORCID 0000-0001-9066-0675
Eduardo Antonio Ferraz CoelhoPrograma de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0002-6681-9014
Miguel Angel Chávez-FumagalliComputational Biology and Chemistry Research Group, Vicerrectorado de Investigación, Universidad Católica de Santa María, Arequipa 04000, Peru.ORCID 0000-0002-8394-4802

Funding

ProCiencia PE501088204-2024Universidad Catolica de Santa Maria 27499-R-2020, 27574-R-2020, 7309-CU-2020, and 28048-R-2021
6 · The paper itself

Abstract

Leishmaniasis, a neglected tropical disease caused by

Indexed as

Antiprotozoal AgentsLeishmaniaNaphthoquinonesAmphotericin BAnimalsComputer SimulationInhibitory Concentration 50Leishmania infantumLeishmaniasisMiceMolecular Docking SimulationParasitic Sensitivity TestsAmphotericin BAntiprotozoal AgentsNaphthoquinonesantileishmanial activityarginase inhibitioncytotoxicityechioidininleishmaniasismalvidin

Identifiers

PMID39795229
PMCPMC11722285

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.