Evidence map›Paper›PMID 39796020›Full record

ArticleInternational journal of molecular sciences2024

Dyspareunia and Biomarkers: A Case Study of Sexual Dysfunction in Moderate Endometriosis.

Ionel Daniel Nati, Razvan Ciortea, Andrei Malutan, Mihaela Oancea, Cristian Iuhas, Carmen Bucuri, Maria Roman, Cristina Ormindean, Leon Gombos, Dan Mihu

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ionel Daniel Nati2nd Department of Obstetric and Ginecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400610 Cluj-Napoca, Romania.
Razvan Ciortea2nd Department of Obstetric and Ginecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400610 Cluj-Napoca, Romania.
Andrei Malutan2nd Department of Obstetric and Ginecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400610 Cluj-Napoca, Romania.
Mihaela Oancea2nd Department of Obstetric and Ginecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400610 Cluj-Napoca, Romania.
Cristian Iuhas2nd Department of Obstetric and Ginecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400610 Cluj-Napoca, Romania.
Carmen BucuriEmergency Military Clinical Hospital "Dr Constantin Papilian", 400610 Cluj-Napoca, Romania.
Maria Roman2nd Department of Obstetric and Ginecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400610 Cluj-Napoca, Romania.
Cristina Ormindean2nd Department of Obstetric and Ginecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400610 Cluj-Napoca, Romania.
Leon GombosFaculty of Physical Education and Sport, Bogdan-Vodă University of Cluj Napoca, 400394 Cluj-Napoca, Romania.
Dan Mihu2nd Department of Obstetric and Ginecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400610 Cluj-Napoca, Romania.

Funding

Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania 881/34/12.01.2022
6 · The paper itself

Abstract

Endometriosis, a chronic hormone-dependent condition affecting 10% of women globally, impacts pelvic organs and occasionally distant sites, causing pain, infertility, and sexual dysfunction. Biomarkers such as IL-8, IL-10, and BDNF influence inflammation, nerve sensitization, and pain. This study investigates their relationship with sexual quality of life, focusing on dyspareunia and related dysfunctions, as assessed using the Female Sexual Function Index (FSFI). Dyspareunia, a prominent symptom of endometriosis, is linked to lower FSFI scores in domains such as desire (mean 3.38), satisfaction (mean 3.28), and pain (mean 3.07). Elevated IL-8 tissue levels negatively correlated with desire (r = -0.649,

Indexed as

BiomarkersDyspareuniaEndometriosisSexual Dysfunction, PhysiologicalAdultBrain-Derived Neurotrophic FactorFemaleHumansInterleukin-10Interleukin-8Middle AgedQuality of LifeBDNF protein, humanBiomarkersBrain-Derived Neurotrophic FactorInterleukin-10Interleukin-8dyspareuniaendometriosislubricationsexual function

Identifiers

PMID39796020
PMCPMC11720033

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.