Evidence map›Paper›PMID 39796175›Full record

ReviewInternational journal of molecular sciences2025

The Emerging Predictive and Prognostic Role of Aggressive-Variant-Associated Tumor Suppressor Genes Across Prostate Cancer Stages.

Martino Pedrani, Jessica Barizzi, Giuseppe Salfi, Alessandro Nepote, Irene Testi, Sara Merler, Luis Castelo-Branco, Ricardo Pereira Mestre, Fabio Turco, Luigi Tortola and 3 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Martino PedraniOncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.ORCID 0000-0002-8502-8226
Jessica BarizziIstituto Cantonale di Patologia, Ente Ospedaliero Cantonale (EOC), 6600 Locarno, Switzerland.
Giuseppe SalfiOncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.ORCID 0000-0003-4953-0339
Alessandro NepoteOncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.
Irene TestiOncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.
Sara MerlerOncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.ORCID 0000-0002-8691-6284
Luis Castelo-BrancoOncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.
Ricardo Pereira MestreOncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.ORCID 0000-0002-3123-3697
Fabio TurcoOncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.
Luigi TortolaOncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.
Jean-Philippe TheurillatInstitute of Oncology Research (IOR), 6500 Bellinzona, Switzerland.
Silke GillessenOncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.ORCID 0000-0001-5746-6555
Ursula VoglOncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale (EOC), 6500 Bellinzona, Switzerland.ORCID 0000-0002-2046-4246

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aggressive variant prostate cancer (AVPC) is characterized by a molecular signature involving combined defects in

Indexed as

Biomarkers, TumorProstatic NeoplasmsPTEN PhosphohydrolaseGenes, Tumor SuppressorHumansMaleNeoplasm StagingPrognosisTumor Suppressor Protein p53Biomarkers, TumorPTEN PhosphohydrolasePTEN protein, humanTumor Suppressor Protein p53aggressive variant prostate cancer (AVPC)predictiveprognosisprostate cancerPTENRB1targetingTP53tumor suppressor genes (TSGs)

Identifiers

PMID39796175
PMCPMC11719667

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.