Evidence map›Paper›PMID 39796632›Full record

ArticleNutrients2025

Exploring the Role of Glycine Metabolism in Coronary Artery Disease: Insights from Human Genetics and Mouse Models.

Subarna Biswas, James R Hilser, Nicholas C Woodward, Zeneng Wang, Janet Gukasyan, Ina Nemet, William S Schwartzman, Pin Huang, Yi Han, Zachary Fouladian and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Subarna BiswasDepartment of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0003-1868-3500
James R HilserDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0001-5849-7839
Nicholas C WoodwardDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Zeneng WangDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-6455-8228
Janet GukasyanDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Ina NemetDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-0657-7121
William S SchwartzmanDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Pin HuangDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Yi HanDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Zachary FouladianDepartment of Medicine, David Geffen School of Medicine of UCLA, Los Angeles, CA 90095, USA.ORCID 0000-0003-1447-8884
Sarada CharugundlaDepartment of Medicine, David Geffen School of Medicine of UCLA, Los Angeles, CA 90095, USA.
Neal J SpencerDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0009-0006-3911-2706
Calvin PanDepartment of Human Genetics, David Geffen School of Medicine of UCLA, Los Angeles, CA 90095, USA.
W H Wilson TangDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-8335-735X
Aldons J LusisDepartment of Medicine, David Geffen School of Medicine of UCLA, Los Angeles, CA 90095, USA.ORCID 0000-0001-9013-0228
Stanley L HazenDepartment of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Jaana A HartialaDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0003-4883-9318
Hooman AllayeeDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0002-2384-5239

Funding

Pilot Projects ProgramP30ES007048 · UNIVERSITY OF SOUTHERN CALIFORNIA · 1996 to 2025
$10.4M
Structural Determinants of Ceruloplasmin Inflammatory ActivityP01HL076491 · CLEVELAND CLINIC LERNER COL/MED-CWRU · 2004 to 2005
$3.6M
The impact of estrogen receptor alpha on cardiomyocellular metabolism and healthU54HL170326 · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2025 to 2025
$1.5M
Genetic Predisposition to Myocardial Infarction in Patients with Coronary Artery DiseaseR01HL168493 · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2025 to 2025
$709k
NHLBI NIH HHS P01 HL076491NHLBI NIH HHS P01 HL098055NHLBI NIH HHS P01 HL147823NHLBI NIH HHS R01 HL103931NHLBI NIH HHS R01 HL133169NHLBI NIH HHS R01 HL148110NHLBI NIH HHS R01 HL168493NHLBI NIH HHS U54 HL170326NIDDK NIH HHS U54 DK120342NIEHS NIH HHS P30 ES007048NIH HHS P30ES007048NIH HHS R01HL133169NIH HHS R01HL14811NIH HHS R01HL168493NIH HHS U54HL170326
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Coronary Artery DiseaseGlycineAgedAnimalsAtherosclerosisDietary SupplementsDisease Models, AnimalFemaleGenome-Wide Association StudyHumansMaleMendelian Randomization AnalysisMiceMice, Knockout, ApoEMiddle AgedPolymorphism, Single NucleotideGlycineatherosclerosiscoronary artery diseasedietary supplementationgenome-wide association studyglycineMendelian randomizationmice

Identifiers

PMID39796632
PMCPMC11723402

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.