Evidence map›Paper›PMID 39796670›Full record

ArticleCancers2024

Clinically Significant

Răzvan Mihail Pleșea, Anca-Lelia Riza, Ana Maria Ahmet, Ionuț Gavrilă, Andreea Mituț, Georgiana-Cristiana Camen, Cristian Virgil Lungulescu, Ștefania Dorobanțu, Adina Barbu, Andra Grigorescu and 4 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Răzvan Mihail PleșeaRegional Centre of Medical Genetics Dolj, Emergency County Hospital Craiova, 200642 Craiova, Romania.ORCID 0000-0003-2686-3878
Anca-Lelia RizaRegional Centre of Medical Genetics Dolj, Emergency County Hospital Craiova, 200642 Craiova, Romania.
Ana Maria AhmetDoctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Ionuț GavrilăRegional Centre of Medical Genetics Dolj, Emergency County Hospital Craiova, 200642 Craiova, Romania.
Andreea MituțRegional Centre of Medical Genetics Dolj, Emergency County Hospital Craiova, 200642 Craiova, Romania.
Georgiana-Cristiana CamenDepartment of Radiology and Medical Imaging, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Cristian Virgil LungulescuDepartment of Medical Oncology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Ștefania DorobanțuRegional Centre of Medical Genetics Dolj, Emergency County Hospital Craiova, 200642 Craiova, Romania.
Adina BarbuRegional Centre of Medical Genetics Dolj, Emergency County Hospital Craiova, 200642 Craiova, Romania.
Andra GrigorescuLaboratory of Human Genomics, University of Medicine and Pharmacy of Craiova, 200638 Craiova, Romania.
Cecil Sorin MireaDepartment of Surgical Semiology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Michael SchenkerDepartment of Medical Oncology, Sfantul Nectarie Oncology Center, 200801 Dolj, Romania.
Florin BuradaRegional Centre of Medical Genetics Dolj, Emergency County Hospital Craiova, 200642 Craiova, Romania.
Ioana StreațăRegional Centre of Medical Genetics Dolj, Emergency County Hospital Craiova, 200642 Craiova, Romania.

Funding

Craiova University of Medicine and Pharmacy Internal Grant no.23/516/54/ 16.05.2022
6 · The paper itself

Abstract

backgroundConditions associated with MATERIALS AND

methodsThe study involved 58 patients with a personal and familial history of breast cancer (BC) who underwent genetic testing at the Regional Centre for Medical Genetics Dolj over a three-year period. An immunohistochemical panel (HER2, ER, PR, and Ki-67) was used to define the molecular subtypes of breast tumors. The AmpliSeq for Illumina

resultsOur findings revealed that 15.5% of the patients carried either

conclusionsThe study revealed that PVs in both BRCA genes have a significant frequency among BC patients in our region, and

Indexed as

BRCA1BRCA2breast cancergenetic susceptibility

Identifiers

PMID39796670
PMCPMC11718772

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.