Evidence map›Paper›PMID 39797666›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2025

Cold exposure and thermoneutrality similarly reduce supraclavicular brown adipose tissue fat fraction in fasted young lean adults.

Robin van Eenige, Carlijn A Hoekx, Aashley S D Sardjoe Mishre, Maaike E Straat, Mariëtte R Boon, Borja Martinez-Tellez, Patrick C N Rensen, Hermien E Kan

Abstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Motion-robust proton density fat fraction andMagma (New York, N.Y.) · 2026
    Article
  2. Cold exposure and thermoneutrality similarly reduce supraclavicular brown adipose tissue fat fraction in fasted young lean adults.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robin van EenigeDivision of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0003-2637-3801
Carlijn A HoekxDivision of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-6941-7339
Aashley S D Sardjoe MishreDepartment of Radiology, C.J. Gorter MRI Center, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-8813-4876
Maaike E StraatDivision of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-3148-8358
Mariëtte R BoonDivision of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-3247-7538
Borja Martinez-TellezDivision of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0001-8783-1859
Patrick C N RensenDivision of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-8455-4988
Hermien E KanDepartment of Radiology, C.J. Gorter MRI Center, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-5772-7177

Funding

British Heart FoundationDutch and British Heart Foundation 02-001-2021-B020Leiden University Medical Center LUMC profile area "biomedical imaging"Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO) 09150161910073Netherlands Cardiovascular Research Initiative CVON2017
6 · The paper itself

Abstract

Brown adipose tissue (BAT) is a metabolically highly active tissue that dissipates energy stored within its intracellular triglyceride droplets as heat. Others have previously utilized MRI to show that the fat fraction of human supraclavicular BAT (scBAT) decreases upon cold exposure, compared with baseline (i.e., pre-cooling). However, comparisons to a control group that was not exposed to cold are largely lacking. We recently developed a non-invasive dynamic MRI protocol that allows for quantifying scBAT fat fraction changes over time. Here, we aimed to study the effect of cold exposure versus thermoneutrality on fat fraction changes in human scBAT. Ten young (mean age: 21.5 ± 0.7 years), lean (mean BMI: 21.7 ± 0.5 kg/m

Indexed as

Adipose Tissue, BrownCold TemperatureFastingAdultCross-Over StudiesFemaleHumansMagnetic Resonance ImagingMaleYoung Adultbrown adipose tissuecold exposurefat fractionmagnetic resonance imaging

Identifiers

PMID39797666
PMCPMC11724390

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.