Evidence map›Paper›PMID 39797961›Full record

ReviewCurrent obesity reports2025

Nutritional Strategies for Battling Obesity-Linked Liver Disease: the Role of Medical Nutritional Therapy in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Management.

Daniel Simancas-Racines, Giuseppe Annunziata, Ludovica Verde, Federica Fascì-Spurio, Claudia Reytor-González, Giovanna Muscogiuri, Evelyn Frias-Toral, Luigi Barrea

Abstract readReview
In one paragraph

Review in Current obesity reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  10. Nutrition and longevity - diet in centenarians.Journal of translational medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel Simancas-RacinesUniversidad UTE, Facultad de Ciencias de la Salud Eugenio Espejo, Centro de Investigación en Salud Pública y Epidemiología Clínica (CISPEC), Quito, 170527, Ecuador. dsimancas@ute.edu.ec.ORCID http://orcid.org/0000-0002-3641-1501
Giuseppe AnnunziataFacoltà di Scienze Umane, della Formazione e dello Sport, Università Telematica Pegaso, Via Porzio, Centro Direzionale, Isola F2, Naples, 80143, Italy.ORCID http://orcid.org/0000-0002-1922-662X
Ludovica VerdeDepartment of Public Health, University of Naples Federico II, Naples, Italy.ORCID http://orcid.org/0000-0002-4583-8283
Federica Fascì-SpurioGastroenterology Unit, Ospedale Dell'Angelo, Venice, Italy.ORCID http://orcid.org/0009-0006-0998-3332
Claudia Reytor-GonzálezUniversidad UTE, Facultad de Ciencias de la Salud Eugenio Espejo, Centro de Investigación en Salud Pública y Epidemiología Clínica (CISPEC), Quito, 170527, Ecuador.ORCID http://orcid.org/0009-0007-4234-5524
Giovanna MuscogiuriUnità di Endocrinologia, Diabetologia e Andrologia, Dipartimento di Medicina Clinica e Chirurgia, Università degli Studi di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.ORCID http://orcid.org/0000-0002-8809-4931
Evelyn Frias-ToralUniversidad Espíritu Santo, Escuela de Medicina, Samborondón, 0901952, Ecuador. evelynft@gmail.com.ORCID http://orcid.org/0000-0002-2228-0141
Luigi BarreaDipartimento Psicologia e Scienze della Salute, Università Telematica Pegaso, Centro Direzionale Isola F2, Via Porzio, Naples, 80143, Italy.ORCID http://orcid.org/0000-0001-9054-456X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis narrative review explores the role of Medical Nutritional Therapy (MNT) in managing Metabolic-Associated Steatotic Liver Disease (MASLD), previously known as nonalcoholic fatty liver disease. It aims to examine the effectiveness of specific nutritional strategies in preventing and treating this obesity-linked liver disease. RECENT

findingsEmerging evidence underscores the benefits of the Mediterranean diet, low-carbohydrate diets, and intermittent fasting in reducing liver fat, improving insulin sensitivity, and mitigating inflammation. Supplementing with vitamin E, omega-3 fatty acids, and silymarin can potentially reduce liver fibrosis and promote liver health. MNT is a key intervention for MASLD management, emphasizing dietary patterns, caloric restriction, and nutraceutical supplementation. Integrating these strategies with lifestyle modifications, including regular physical activity, offers a comprehensive approach to improving metabolic and liver outcomes in patients with MASLD. Further research is needed to refine and personalize these therapeutic interventions.

Indexed as

Dietary SupplementsDiet, MediterraneanNon-alcoholic Fatty Liver DiseaseObesityCaloric RestrictionDiet, Carbohydrate-RestrictedFatty Acids, Omega-3HumansInsulin ResistanceNutrition TherapyFatty Acids, Omega-3Liver fibrosisMedical Nutritional Therapy (MNT)Mediterranean dietMetabolic-Associated Steatotic Liver Disease (MASLD)Nutraceutical supplementationObesity

Identifiers

PMID39797961
PMCPMC11724794

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.