Evidence map›Paper›PMID 39801523›Full record

ArticleResearch square2024

Malaria among febrile patients suspected of Yellow fever during an outbreak in Ghana.

Lidiwan Mensah, Anisa Abdulai, Gloria Amegatcher, Deborah Pratt, Evans Aduhene, Magdalene Sarah Nketia Ofori, Abdul Rahim Mohammed Sabtiu, Patience Adams, Prince Ketorwoley, Christopher Mfum Owusu-Asenso and 4 more

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Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Lidiwan MensahDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana.
Anisa AbdulaiCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana.
Gloria AmegatcherDepartment of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana.
Deborah PrattDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana.
Evans AduheneCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana.
Magdalene Sarah Nketia OforiDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana.
Abdul Rahim Mohammed SabtiuCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana.
Patience AdamsDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana.
Prince KetorwoleyDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana.
Christopher Mfum Owusu-AsensoCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana.
Nana Aba Setorwu EyesonCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana.
Kwamena William Coleman SagoeCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana.
Joseph Humphrey Kofi BonneyDepartment of Virology, Noguchi Memorial Institute for Medical Research, University of Ghana.
Yaw Asare AfraneCentre for Vector-Borne Disease Research, Department of Medical Microbiology, University of Ghana Medical School, University of Ghana.

Funding

Regional Centre for Vector Borne Diseases in West Africa (RCVBD)D43TW011513 · FIC · UNIVERSITY OF GHANA · PI YAW ASARE AFRANE, Guiyun Yan · 2021 to 2026
$1.5M
FIC NIH HHS D43 TW011513
6 · The paper itself

Abstract

Introduction: Between October 2021 and February 2022, there was an outbreak of Yellow fever that spread within several districts in the northern part of Ghana. Febrile illnesses such as Yellow fever are often misdiagnosed as malaria and vice versa, which delays appropriate management and treatment. Hence, the true burden of Yellow fever and malaria are mostly underestimated. This study investigated the epidemiology of malaria in febrile patients suspected of Yellow fever in and around the epicenter of a Yellow fever outbreak in Ghana. Methods: The study was a cross-sectional study conducted in two outbreak sites (Wenchi and Damongo) and two non-outbreak sites (Kumbungu and Tamale). A total of 498 febrile patients from healthcare facilities were recruited in the rainy and dry seasons. A structured questionnaire was administered to collect patients' demographic information. Venous blood was collected from consented study participants for malaria parasite detection via microscopy and PCR. Total RNA was extracted from serum samples for the detection of yellow fever virus using Reverse Transcriptase PCR. Results: None of the patients tested positive for Yellow fever virus. Out of the 498 participants tested for plasmodium parasites, 98 (19.7%) were microscopy positive while 92 (29.7%) were PCR positive. Plasmodium prevalence via microscopy was significantly higher in the dry season, 42 (18.67%) compared to the rainy season, 12 (4.4%) ( Conclusion: High malaria prevalence was found in the study sites, affecting preschool and the school-aged children the most. Although Yellow fever was not detected, its overlap with malaria in Ghana, suggests the importance of enhancing surveillance for both diseases to better prevent and control.

Indexed as

GhanaMalariaMicroscopyPCRYellow fever

Identifiers

PMID39801523
PMCPMC11722538

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.