Evidence map›Paper›PMID 39801740›Full record

ArticleImmune network2024

Simultaneous Epigenetic and Gene Expression Profiling at Single Cell Resolution Uncovers Stem-Like Treg Subsets Induced With Oligonucleotide Expansion in Humans.

Hyo Jeong Nam, Jeong-Ryeol Gong, Yong-Hee Kim, Thuy Nguyen-Phuong, Nari Byun, Jeong Heon Yoon, Yong Chan Kim, Hyunwoo Chung, Brian Hyohyoung Lee, Haeyoon Kwon and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immune network, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hyo Jeong NamDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0003-4987-0747
Jeong-Ryeol GongDepartment of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Korea.ORCID https://orcid.org/0000-0001-7057-4489
Yong-Hee KimDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0001-6282-2980
Thuy Nguyen-PhuongDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0002-8782-8163
Nari ByunDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0002-0508-6910
Jeong Heon YoonTeraimmune, Inc., Gaithersburg, MD 20878, USA.
Yong Chan KimTeraimmune, Inc., Gaithersburg, MD 20878, USA.
Hyunwoo ChungDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0001-9103-0560
Brian Hyohyoung LeeDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0002-1291-3208
Haeyoon KwonDepartment of Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0009-0001-3422-0007
Woochan LeeGenomic Medicine Institute, Medical Research Center, Seoul National University, Seoul 03080, Korea.ORCID https://orcid.org/0000-0002-1092-7331
Sung-Jun KangDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0001-8126-4072
Kyunghyuk ParkGenomic Medicine Institute, Medical Research Center, Seoul National University, Seoul 03080, Korea.ORCID https://orcid.org/0000-0002-3141-5087
Bukyoung ChaGenomic Medicine Institute, Medical Research Center, Seoul National University, Seoul 03080, Korea.ORCID https://orcid.org/0000-0002-2859-0685
Jong-Il KimDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0002-7240-3744
Hyun Je KimDepartment of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID https://orcid.org/0000-0003-4467-0949

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tregs play a central role in maintaining immune tolerance. Recent progress in the clinical application of Tregs underscores their potential for cell therapy. Nevertheless, a notable hurdle remains in producing functional Tregs

Indexed as

EpigeneticsRegulatory T cellTranscriptomics

Identifiers

PMID39801740
PMCPMC11711129

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.