Evidence map›Paper›PMID 39803408›Full record

ReviewTaiwan journal of ophthalmology

Utility of multimodal imaging in the clinical diagnosis of inherited retinal degenerations.

Brian J H Lee, Christopher Z Y Sun, Charles J T Ong, Kanika Jain, Tien-En Tan, Choi Mun Chan, Ranjana S Mathur, Rachael W C Tang, Yasmin Bylstra, Sylvia P R Kam and 2 more

Abstract readReview
In one paragraph

Review in Taiwan journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. To see with new eyes.Taiwan journal of ophthalmology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Brian J H LeeSingapore National Eye Centre, Singapore Eye Research Institute, Singapore.
Christopher Z Y SunSingapore National Eye Centre, Singapore Eye Research Institute, Singapore.
Charles J T OngSingapore National Eye Centre, Singapore Eye Research Institute, Singapore.
Kanika JainGenome Institute of Singapore, Singapore.
Tien-En TanSingapore National Eye Centre, Singapore Eye Research Institute, Singapore.
Choi Mun ChanSingapore National Eye Centre, Singapore Eye Research Institute, Singapore.
Ranjana S MathurSingapore National Eye Centre, Singapore Eye Research Institute, Singapore.
Rachael W C TangSingapore National Eye Centre, Singapore Eye Research Institute, Singapore.
Yasmin BylstraSingHealth-Duke-NUS Genomic Medicine Centre, Institute of Precision Medicine, Singapore.
Sylvia P R KamDepartment of Paediatrics, KK Women's and Children's Hospital, Singapore.
Weng Khong LimSingHealth-Duke-NUS Genomic Medicine Centre, Institute of Precision Medicine, Singapore.
Beau J FennerSingapore National Eye Centre, Singapore Eye Research Institute, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inherited retinal degeneration (IRD) is a heterogeneous group of genetic disorders of variable onset and severity, with vision loss being a common endpoint in most cases. More than 50 distinct IRD phenotypes and over 280 causative genes have been described. Establishing a clinical phenotype for patients with IRD is particularly challenging due to clinical variability even among patients with similar genotypes. Clinical phenotyping provides a foundation for understanding disease progression and informing subsequent genetic investigations. Establishing a clear clinical phenotype for IRD cases is required to corroborate the data obtained from exome and genome sequencing, which often yields numerous variants in genes associated with IRD. In the current work, we review the use of contemporary retinal imaging modalities, including ultra-widefield and autofluorescence imaging, optical coherence tomography, and multispectral imaging, in the diagnosis of IRD.

Indexed as

Autofluorescenceimaginginherited retinal degenerationinherited retinal diseaseoptical coherence tomographyretina

Identifiers

PMID39803408
PMCPMC11717338

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.