Evidence map›Paper›PMID 39803495›Full record

ArticlebioRxiv : the preprint server for biology2025

Nuclear basket proteins Nup2 and Mlp1 drive heat shock-induced 3D genome restructuring downstream of transcriptional activation.

Suman Mohajan, Linda S Rubio, David S Gross

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Suman MohajanDepartment of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130.ORCID 0000-0002-8913-9425
Linda S RubioDepartment of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130.ORCID 0000-0002-7260-6971
David S GrossDepartment of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130.ORCID 0000-0002-7957-8790

Funding

Genome Architecture and Gene Control in Response to StressR01GM138988 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI GROSS, DAVID SAMUEL · 2020 to 2023
$1.2M
Role of Actin in the Chromosomal Conformation & Nuclear Organization of HSP GenesR15GM128065 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI GROSS, DAVID SAMUEL · 2018 to 2019
$523k
NIGMS NIH HHS R01 GM138988NIGMS NIH HHS R15 GM128065
6 · The paper itself

Abstract

The nuclear pore complex (NPC), a multisubunit complex located within the nuclear envelope, regulates RNA export and the import and export of proteins. Here we address the role of the NPC in driving thermal stress-induced 3D genome repositioning of

Indexed as

3D genome architecturechromatinHeat Shock Factor (Hsf1)Heat Shock ResponseMlp1Nuclear Pore ComplexNup1Nup145Nup2RNA Pol IISaccharomyces cerevisiaetranscriptional condensates

Identifiers

PMID39803495
PMCPMC11722380

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.