Evidence map›Paper›PMID 39803498›Full record

ArticlebioRxiv : the preprint server for biology2024

Gut Bacteria Encode Reductases that Biotransform Steroid Hormones.

Gabriela Arp, Angela Jiang, Keith Dufault-Thompson, Sophia Levy, Aoshu Zhong, Jyotsna Talreja Wassan, Maggie Grant, Yue Li, Brantley Hall, Xiaofang Jiang

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Gabriela ArpDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, College Park, Maryland, USA.
Angela JiangDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, College Park, Maryland, USA.
Keith Dufault-ThompsonNational Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.
Sophia LevyDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, College Park, Maryland, USA.
Aoshu ZhongDivision of Molecular and Cellular Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.
Jyotsna Talreja WassanNational Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.
Maggie GrantDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, College Park, Maryland, USA.
Yue LiDepartment of Chemistry and Biochemistry, University of Maryland, College Park, College Park, Maryland, USA.
Brantley HallDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, College Park, Maryland, USA.
Xiaofang JiangNational Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA.

Funding

Enzymatic Determinants of Gut Microbial Metabolic BiotransformationsR35GM155208 · UNIV OF MARYLAND, COLLEGE PARK · 2025 to 2025
$390k
NIGMS NIH HHS R35 GM155208
6 · The paper itself

Abstract

The metabolism of steroids by the gut microbiome affects hormone homeostasis, impacting host development, mental health, and reproductive functions. In this study, we identify the Δ

Indexed as

metabolismmicrobial biotransformationprogesteronereductasessteroid hormones

Identifiers

PMID39803498
PMCPMC11722256

What Socratic holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.