Evidence map›Paper›PMID 39806949›Full record

ReviewCurrent molecular medicine2025

An Overview of Invasive Ductal Carcinoma (IDC) in Women's Breast Cancer.

Adriana E Gallas, Grace O Morenikeji, Raven E King, Muyiwa S Adegbaju, Adeola Ayoola, Godstime Taiwo, Olanrewaju B Morenikeji

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adriana E GallasDivision of Biological and Health Sciences, University of Pittsburgh, 300 Campus Drive, Bradford PA 16701, USA.
Grace O MorenikejiDivision of Biological and Health Sciences, University of Pittsburgh, 300 Campus Drive, Bradford PA 16701, USA.
Raven E KingDivision of Biological and Health Sciences, University of Pittsburgh, 300 Campus Drive, Bradford PA 16701, USA.
Muyiwa S AdegbajuDepartment of Biomedical Sciences, College of Health Science and Technology, Rochester Institute of Technology, Rochester, Rochester, NY 14302, USA.
Adeola AyoolaDepartment of Evolutionary Anthropology, Duke University, Durham, NC 27708, USA.
Godstime TaiwoDepartment of Pediatrics, University of California San Francisco, Oakland, California, USA.
Olanrewaju B MorenikejiDivision of Biological and Health Sciences, University of Pittsburgh, 300 Campus Drive, Bradford PA 16701, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Invasive ductal carcinoma (IDC) is the most common type of breast cancer, primarily affecting women in the United States and across the world. This review summarizes key concepts related to IDC causes, treatment approaches, and the identification of biological markers for specific prognoses. Furthermore, we reviewed many studies, including those involving patients with IDC and ductal carcinoma in situ (DCIS) that progressed to IDC. We reported various studies on the causes of IDC, including mutations on BRCA1 and BRCA2, different levels of expression of specific genes in signaling pathways, menopause status, alcohol consumption, aging, and hormone imbalances that cause IDC while p-SMAD4 expressions, DNA methylation, regulations of hub genes, and underestimation of IDC affecting prognoses. Prompt IDC diagnosis and early intervention have been reported to demonstrate a greater probability of eradicating IDC and preventing further recurrence in the future. It is crucial for physicians and researchers to equip patients with the best information possible to proactively manage their health, whether it be for IDC prevention or treatment. Overall, our review provided a comprehensive understanding of IDC that enables patients to grasp the nature of the disease with the hope of mitigating IDC risk, decrease the anxiety of a cancer diagnosis, and encourage patients to become more involved in making informed decisions for their healthcare.

Indexed as

Breast NeoplasmsCarcinoma, Ductal, BreastBiomarkers, TumorDNA MethylationFemaleGene Expression Regulation, NeoplasticHumansMutationPrognosisBiomarkers, Tumorbreast cancercancer treatmentscarcinomasDCIS.IDCInvasive ductal carcinoma

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.