Evidence map›Paper›PMID 39807061›Full record

ArticleClinical and experimental emergency medicine2025

The landscape of experimental cardiac arrest research models in rats: a bibliometric analysis of the 100 most cited articles.

Georgios Mavrovounis, Maria Mermiri, Ioannis Drivas, Konstantinos Drivas, Theodosis Kalamatianos, Sotirios G Zarogiannis, Ioannis Pantazopoulos

Abstract read
In one paragraph

Article in Clinical and experimental emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Georgios MavrovounisDepartment of Emergency Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Maria MermiriDepartment of Anesthesiology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Ioannis DrivasDepartment of Emergency Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Konstantinos DrivasDepartment of Emergency Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Theodosis KalamatianosDepartment of Neurosurgery, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.
Sotirios G ZarogiannisDepartment of Physiology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.
Ioannis PantazopoulosDepartment of Emergency Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This bibliometric analysis of the 100 most cited articles on experimental cardiac arrest models in rats identifies key contributors, publication trends, research themes, and collaboration networks. A comprehensive literature search of the Web of Science database was performed on June 11, 2024, using keywords related to cardiac arrest and rat models. The top 100 most cited articles were analyzed using the biblioshiny web application from the bibliometrix R ver. 4.2.3 and categorized by primary research focus. The articles were published from 1980 to 2022 and involved 416 authors and 44 journals, averaging 106.7 citations each. The primary research themes were neurology (72%), organ transplantation (7%), cardiovascular system (6%), Cardiopulmonary resuscitation outcomes after local anesthetic toxicity (4%), and other topics (5%). The United States, Japan, and Germany were leading contributors. Major clusters identified include "cerebral ischemia and outcomes," "brain imaging metrics," and "blood brain barrier." The most commonly used methodologies for cardiac arrest induction were asphyxia, induction by magnesium or potassium chloride, and electrical stimulation. This first bibliometric analysis on this topic reveals the dominance of neuroscience in experimental cardiac arrest models in rats. High-impact journals such as the Journal of Cerebral Blood Flow and Metabolism play critical roles in disseminating significant research. The study highlights substantial gaps in global research engagement, with minimal contributions from lower income countries and few international collaborations. This analysis provides a roadmap for future research and opportunities for more extensive international and interdisciplinary collaboration, always with a focus on scientific rigor.

Indexed as

Cardiac arrest modelsCardiopulmonary resuscitationExperimental cardiac arrestHeart arrestRats

Identifiers

PMID39807061
PMCPMC12541529

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.