ArticleiScience2025
Supplementary motor area in speech initiation: A large-scale intracranial EEG evaluation of stereotyped word articulation.
Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed.
- Individual differences in speech monitoring: Functional and structural correlates of delayed auditory feedback.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Investigating acoustic startle priming-induced cortical network reorganization in post-stroke dysarthria: a fNIRS study.Biomedical optics express · 2026Article
- Syntactic Processing in the Aging Brain: Neural Reorganization, Cognitive Scaffolding, and Implications for Language Resilience.Brain sciences · 2026Review
- Individual Differences in Global Cognition Modulate the Effect of Motor-Relatedness on Object Naming in Healthy Older Adults.Behavioral sciences (Basel, Switzerland) · 2025Article
- Functional Roles of Sensorimotor Alpha and Beta Oscillations in Overt Speech Production.bioRxiv : the preprint server for biology · 2024Article
- The speech neuroprosthesis.Nature reviews. Neuroscience · 2024Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Speech production engages a distributed network of cortical and subcortical brain regions. The supplementary motor area (SMA) has long been thought to be a key hub in coordinating across these regions to initiate voluntary movements, including speech. We analyzed direct intracranial recordings from 115 patients with epilepsy as they articulated a single word in a subset of trials from a picture-naming task. We aimed to characterize the temporal dynamics of SMA relative to other cortical regions. SMA and preSMA were among the first regions to activate after cue onset, peaked in activity before articulation onset, and were the earliest regions to predict trial-to-trial response time. Neural activity at single electrodes in SMA and preSMA was closely associated with speech initiation; activity began at a highly predictable time after stimulus onset and extended until speech onset for any given trial. Our results support the idea that SMA is a key node in the speech initiation network.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.