Developing Mobile Health Applications for Inflammatory Bowel Disease: A Systematic Review of Features and Technologies.

Background: Patients with inflammatory bowel disease (IBD) require lifelong treatment, which significantly impacts their quality of life. Self-management of this disease is an effective factor in managing chronic conditions and improving patients' quality of life. The use of mobile applications is a novel approach to providing self-management models and healthcare services for patients with IBD. The present systematic review aimed to identify the features and technologies used in the development of IBD disease management applications. Methods: This systematic review was conducted according to PRISMA guidelines in PubMed, Scopus, and Web of Sciences databases up to August 8, 2023, which included initial searches, screening studies, assessing eligibility and risk of bias, and study selection. The data extraction form was based on the study objectives, including bibliographic information from articles, such as the first author's name, year of publication, country of origin, and details related to mobile health applications, such as the name of the application, features and technologies used, advantages and disadvantages, main outcomes, and other results. The content of the research was analyzed according to the research objectives. Results: In the initial review of four databases, a total of 160 articles were retrieved and subsequently entered into EndNote. After removing duplicates and irrelevant studies based on title, abstract, and full-text assessments, 12 articles were finally selected. The studies were conducted between the years 2015 and 2024. 100% of the applications designed for patients with IBD were aimed at treatment, 83% were for self-management of the disease, and 33% of the applications were intended for disease diagnosis. The features of IBD management applications were categorized into four groups: education, monitoring, counseling, and diagnosis and treatment. Conclusion: Various mobile applications have been developed for the management of IBD, each differing in features and technologies used. While current IBD applications have limited capabilities in diagnosing disease severity, they still hold significant potential in empowering patients through education, counseling, and monitoring. The integration of artificial intelligence and decision support systems may enhance the effectiveness and reliability of these applications.