Evidence map›Paper›PMID 39809887›Full record

ArticleCellular & molecular immunology2025

Myelin debris as an initiator of microglial dysfunction and neuropathology in Alzheimer's disease.

Joshua D Samuels, John R Lukens

Abstract readLetter
In one paragraph

Article in Cellular & molecular immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joshua D SamuelsCenter for Brain Immunology and Glia (BIG), Department of Neuroscience, University of Virginia (UVA), Charlottesville, VA, 22908, USA. rhk9gh@virginia.edu.ORCID http://orcid.org/0000-0001-5662-3758
John R LukensCenter for Brain Immunology and Glia (BIG), Department of Neuroscience, University of Virginia (UVA), Charlottesville, VA, 22908, USA. jrl7n@virginia.edu.ORCID http://orcid.org/0000-0002-6795-0866

Funding

INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007496 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Michael G. Brown, Coleen A McNamara · 1995 to 2026
$10.2M
Making a case for CASS4 in Alzheimer's diseaseR01AG087406 · NIA · UNIVERSITY OF VIRGINIA · PI John R Lukens · 2024 to 2026
$1.7M
CLEC7A in microglia biology and Alzheimer's diseaseRF1AG078684 · NIA · UNIVERSITY OF VIRGINIA · PI LUKENS, JOHN R · 2023 to 2023
$1.6M
Role of the SYK-CARD9 signaling axis in Alzheimer's diseaseR01AG071996 · NIA · UNIVERSITY OF VIRGINIA · PI LUKENS, JOHN R · 2024 to 2025
$1.1M
Alzheimer's Association ADSF-21-816651NIAID NIH HHS T32 AI007496NIA NIH HHS R01 AG071996NIA NIH HHS R01 AG087406NIA NIH HHS RF1 AG078684U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) T32AI7496U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) R01AG071996U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) R01AG087406U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) RF1AG078684
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39809887
PMCPMC11782469

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.