Evidence mapPaperPMID 39810459Full record

ArticleACS applied bio materials2025

Electrospun Chitosan/Polylactic Acid Nanofibers with Silver Nanoparticles: Structure, Antibacterial, and Cytotoxic Properties.

Yevhen Samokhin, Yuliia Varava, Kateryna Diedkova, Ilya Yanko, Valeriia Korniienko, Yevheniia Husak, Igor Iatsunskyi, Vladlens Grebnevs, Maris Bertiņs, Rafal Banasiuk and 4 more

Abstract read
In one paragraph

Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yevhen SamokhinBiomedical Research Centre, Sumy State University, 116, Kharkivska, 40007 Sumy, Ukraine.
Yuliia VaravaBiomedical Research Centre, Sumy State University, 116, Kharkivska, 40007 Sumy, Ukraine.
Kateryna DiedkovaBiomedical Research Centre, Sumy State University, 116, Kharkivska, 40007 Sumy, Ukraine.
Ilya YankoBiomedical Research Centre, Sumy State University, 116, Kharkivska, 40007 Sumy, Ukraine.ORCID 0000-0001-6926-2461
Valeriia KorniienkoBiomedical Research Centre, Sumy State University, 116, Kharkivska, 40007 Sumy, Ukraine.
Yevheniia HusakFaculty of Chemistry, Silesian University of Technology, 44-100 Gliwice, Poland.
Igor IatsunskyiNanoBioMedical Centre, Adam Mickiewicz University, Wszechnicy Piastowskiej 3, 61-614 Poznan, Poland.
Vladlens GrebnevsFaculty of Chemistry, Silesian University of Technology, 44-100 Gliwice, Poland.
Maris BertiņsFaculty of Chemistry, University of Latvia, Jelgavas iela 1, LV-1004 Riga, Latvia.
Rafal BanasiukNanoWave, 02-676 Warsaw, Poland.
Viktoriia KorniienkoBiomedical Research Centre, Sumy State University, 116, Kharkivska, 40007 Sumy, Ukraine.
Agne RamanaviciuteDepartment of Physical Chemistry, Institute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko Str. 24, LT-03225 Vilnius, Lithuania.
Maksym PogorielovBiomedical Research Centre, Sumy State University, 116, Kharkivska, 40007 Sumy, Ukraine.
Arunas RamanaviciusDepartment of Physical Chemistry, Institute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko Str. 24, LT-03225 Vilnius, Lithuania.ORCID 0000-0002-0885-3556

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrospinning, a technique for creating fabric materials from polymer solutions, is widely used in various fields, including biomedicine. The unique properties of electrospun fibrous membranes, such as large surface area, compositional versatility, and customizable porous structure, make them ideal for advanced biomedical applications like tissue engineering and wound healing. By considering the high biocompatibility and well-known regenerative potential of polylactic acid (PLA) and chitosan (CH), as well as the versatile antibacterial effect of silver nanoparticles (AgNPs), this study explores the antibacterial efficacy, adhesive properties, and cytotoxicity of electrospun chitosan membranes with a unique nanofibrous structure and varying concentrations of AgNPs. Silver nanoparticles incorporated at concentrations of 25-50 μg/mL or above significantly enhanced the antibacterial effectiveness, especially against

Indexed as

Anti-Bacterial AgentsBiocompatible MaterialsChitosanMetal NanoparticlesNanofibersPolyestersSilverCell SurvivalEscherichia coliHumansMaterials TestingMesenchymal Stem CellsMicrobial Sensitivity TestsParticle SizeStaphylococcus aureusAnti-Bacterial AgentsBiocompatible MaterialsChitosanPolyesterspoly(lactide)Silverantibacterial activitybiocompatibilitychitosanelectrospinningnanofiberspolylactic acid

Identifiers

PMID39810459
PMCPMC11836928

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.