Evidence map›Paper›PMID 39811670›Full record

ArticleiScience2025

Mice deficient in TWIK-1 are more susceptible to kainic acid-induced seizures.

Ajung Kim, Yeonju Bae, Changdev G Gadhe, Hyun-Gug Jung, Esther Yang, Hyun Kim, Jaekwang Lee, Chanseob Shim, Young Hoon Sung, Junyeol Noh and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ajung KimBrain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Yeonju BaeBrain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Changdev G GadheConvergence Research Center for Diagnosis, Treatment and Care system of Dementia, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Hyun-Gug JungBrain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Esther YangDepartment of Anatomy, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Hyun KimDepartment of Anatomy, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Jaekwang LeeDivision of Food Functionality, Korea Food Research Institute, Wanju 55365, Republic of Korea.
Chanseob ShimElpis-Biotech, Daejeon 35380, Republic of Korea.
Young Hoon SungConvergence Medicine Research Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul 05505, Republic of Korea.
Junyeol NohSchool of Biosystems and Biomedical Sciences, College of Health Sciences, Korea University, Seoul 02841, Republic of Korea.
Eun-Jin KimDepartment of Physiology and Institute of Medical Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Dawon KangDepartment of Physiology and Institute of Medical Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Republic of Korea.
Ae Nim PaeConvergence Research Center for Diagnosis, Treatment and Care system of Dementia, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Eun Mi HwangBrain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Jae-Yong ParkSchool of Biosystems and Biomedical Sciences, College of Health Sciences, Korea University, Seoul 02841, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TWIK-1 belongs to the two-pore domain K

Indexed as

Biological sciencesMolecular neuroscienceNatural sciencesNeuroscienceSystems neuroscience

Identifiers

PMID39811670
PMCPMC11732521

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.