ArticleNeurology2025
Long-Term Intake of Red Meat in Relation to Dementia Risk and Cognitive Function in US Adults.
Article in Neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Plant-Based Diets and Cognitive Outcomes: A Systematic Review and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2025Pooled it
- The effects of magnesium L-threonate (MagteinFrontiers in nutrition · 2025Trial
- Dietary patterns and exploratory gut microbiota profiles associated with diabetic retinopathy and cognitive impairment in type 2 diabetes.Nutrition & metabolism · 2026Article
- Dietary sialic acid intake and incident dementia: evidence from a large prospective cohort study.European journal of nutrition · 2026Article
- KetoFLEX 12/3 Diet and Cognitive Health: A Precision-Nutrition Perspective on Mechanisms, Emerging Evidence, and Future Directions.Nutrients · 2026Review
- The association between the Prospective Urban Rural Epidemiology (PURE) healthy diet score and cognitive decline in Chinese older adults.NPJ science of food · 2026Article
- Dietary Patterns and Indicators of Cognitive Function.JAMA neurology · 2026Article
- Meat Consumption and Cognitive Health by APOE Genotype.JAMA network open · 2026Article
- Late-life methionine restriction attenuates neuroinflammation in Alzheimer's disease mice via FGF21 activation in a metabolism-independent manner.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Long-term adherence and changes in the Mediterranean and MIND diets in relation to dementia risk and cognitive function.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Perspective: use of beef in a dietary intervention as an effective strategy for improving cognition in young adult females.Frontiers in nutrition · 2026Article
- Effects of Minimally Processed Red Meat within a Plant-Forward Diet on Biomarkers of Physical and Cognitive Aging: A Randomized Controlled Crossover Feeding Trial.Current developments in nutrition · 2026Article
- Association between high carbohydrate to dietary fiber ratio and risk of dementia in older adults: analysis from the UK biobank.BMC neurology · 2025Article
- Review
- A Network Analysis of Food Intake and Cognitive Function in Older Adults with Multimorbidity: A National Cross-Sectional Study.Nutrients · 2025Article
- Animal-derived foods, physical activities, and mild cognitive impairment among Chinese older adults: findings from CLHLS (2008-2018).BMC public health · 2025Article
- Red Meat Amino Acids for Beginners: A Narrative Review.Nutrients · 2025Review
- Temporal trends in dementias in older adults attributable to high fasting plasma glucose from 1990 to 2021 and forecasted disease burden in 2040 in China and globally.Frontiers in public health · 2025Article
- Global patterns linking total meat supply to dementia incidence: A population-based ecological study.AIMS neuroscience · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
BACKGROUND AND
objectivesPrevious studies have shown inconsistent associations between red meat intake and cognitive health. Our objective was to examine the association between red meat intake and multiple cognitive outcomes.
methodsIn this prospective cohort study, we included participants free of dementia at baseline from 2 nationwide cohort studies in the United States: the Nurses' Health Study (NHS) and the Health Professionals Follow-Up Study (HPFS). Diets were assessed using a validated semiquantitative food frequency questionnaire. We ascertained incident dementia cases from both NHS participants (1980-2023) and HPFS participants (1986-2023). Objective cognitive function was assessed using the Telephone Interview for Cognitive Status (1995-2008) among a subset of NHS participants. Subjective cognitive decline (SCD) was self-reported by NHS participants (2012, 2014) and HPFS participants (2012, 2016). Cox proportional hazards models, general linear regression, and Poisson regression models were applied to assess the associations between red meat intake and different cognitive outcomes.
resultsThe dementia analysis included 133,771 participants (65.4% female) with a mean baseline age of 48.9 years, the objective cognitive function analysis included 17,458 female participants with a mean baseline age of 74.3 years, and SCD analysis included 43,966 participants (77.1% female) with a mean baseline age of 77.9 years. Participants with processed red meat intake ≥0.25 serving per day, compared with <0.10 serving per day, had a 13% higher risk of dementia (hazard ratio [HR] 1.13; 95% CI 1.08-1.19; DISCUSSION: Higher intake of red meat, particularly processed red meat, was associated with a higher risk of developing dementia and worse cognition. Reducing red meat consumption could be included in dietary guidelines to promote cognitive health. Further research is needed to assess the generalizability of these findings to populations with diverse ethnic backgrounds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.