Evidence map›Paper›PMID 39814864›Full record

ArticleScientific reports2025

Facial assessment methods for inhibiting glycation and aging effects and the correlation between glycation and aging parameters.

Qin Zhang, Dangdang Cheng, Feifei Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qin ZhangShanghai Jiyan Biomedical Development Co., Ltd., 9th Floor, Building B, No.999 Huaxu Road, Shanghai, 201702, China. zhangqin01@botanee.com.
Dangdang ChengShanghai Jiyan Biomedical Development Co., Ltd., 9th Floor, Building B, No.999 Huaxu Road, Shanghai, 201702, China.
Feifei WangYunnan Characteristic Plant Extraction Laboratory, Yunnan Yunke Characteristic Plant Extraction Laboratory Co., Ltd, Yunnan, 650106, China.

Funding

Yunnan Characteristic Plant Extraction Laboratory 2022YKZY003
6 · The paper itself

Abstract

This study aimed to develop in vivo methods for assessing facial anti-glycation and anti-aging effects and to investigate the link between glycation and aging signs. We utilized an AGE reader to measure AGEs levels on the face and arms, establishing a correlation to validate the reader's use for facial AGEs detection. Then the product's 7-day anti-glycation effect was evaluated. And its 56-day anti-aging effects were evaluated using non-invasive probes and VISIA CR, assessing skin tone (skin brightness L* and yellowness b*, skin gloss), texture (skin elasticity R2 and firmness F4, skin pores), and hydration (skin moisture content). Correlations between facial AGEs levels and aging parameters were analyzed. Results indicated a strong correlation between facial and arm AGEs after product application, supporting facial AGEs level as an assessment parameter. The product demonstrated substantial anti-glycation and anti-aging effects, suggesting the methods' efficacy for cosmetic evaluation. A stronger overall correlation was found between AGEs levels and skin tone than with skin texture and hydration, highlighting glycation's impact on skin color.

Indexed as

AgingCosmeticsFaceGlycation End Products, AdvancedSkin AgingAdultAgedFemaleGlycosylationHumansMaleMiddle AgedSkinSkin PigmentationYoung AdultCosmeticsGlycation End Products, AdvancedAGE readerAnti-aging evaluationAnti-glycation evaluationGlycation-aging correlation

Identifiers

PMID39814864
PMCPMC11735971

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.