Evidence map›Paper›PMID 39814878›Full record

ArticleNature2025

Specification of claustro-amygdalar and palaeocortical neurons and circuits.

Navjot Kaur, Rothem Kovner, Forrest O Gulden, Mihovil Pletikos, David Andrijevic, Tianjia Zhu, John Silbereis, Mikihito Shibata, Akemi Shibata, Yuting Liu and 18 more

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Navjot KaurDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-8514-203X
Rothem KovnerDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
Forrest O GuldenDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
Mihovil PletikosDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
David AndrijevicDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-5703-3837
Tianjia ZhuDepartment of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
John SilbereisDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
Mikihito ShibataDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
Akemi ShibataDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.ORCID 0009-0006-6761-691X
Yuting LiuDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
Shaojie MaInstitute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.ORCID 0000-0002-8782-3047
Nikkita SallaDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-5343-676X
Xabier de MartinNeurogenomics Group, Hospital del Mar Research Institute, PRBB, Barcelona, Spain.
Thomas S KlarićDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0003-1353-1049
Megan BurkeDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.ORCID 0009-0004-2655-5810
Daniel FranjicDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
Hyesun ChoDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0003-1254-768X
Matthew YuenDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
Ipsita ChatterjeeDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
Paula SoricDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
Devippriya EsakkimuthuDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
Markus MoserInstitute of Experimental Hematology, School of Medicine, Techical University of Munich, Munich, Germany.ORCID 0000-0001-8825-5566
Gabriel SantpereDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-5909-8637
Yann S MineurDepartment of Psychiatry, New Haven, CT, USA.
Kartik PattabiramanDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA.
Marina R PicciottoYale Child Study Center, New Haven, CT, USA.ORCID 0000-0002-4404-1280
Hao HuangDepartment of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-9103-4382
Nenad SestanDepartment of Neuroscience, Yale School of Medicine, New Haven, CT, USA. nenad.sestan@yale.edu.ORCID 0000-0003-0966-9619

Funding

Functional Genomics of Human Brain DevelopmentP50MH106934 · NIMH · YALE UNIVERSITY · PI SESTAN, NENAD · 2014 to 2019
$7.9M
RESEARCH TRAINING - BIOLOGICAL SCIENCEST32MH014276 · NIMH · YALE UNIVERSITY · PI Marina R Picciotto · 1985 to 2026
$7.2M
Cholinergic Contribution to Circuits Underlying DepressionR01MH077681 · NIMH · YALE UNIVERSITY · PI MINEUR, YANN SEBASTIEN, PICCIOTTO, MARINA R · 2006 to 2025
$7.0M
1/2 Cell Type and Region-Specific Regulatory Networks in Human Brain Development and DisordersU01MH116488 · NIMH · YALE UNIVERSITY · PI SESTAN, NENAD · 2018 to 2022
$6.5M
Structural Development of Human Fetal BrainR01MH092535 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI HUANG, HAO · 2011 to 2020
$4.6M
Yale Macaque Brain ResourceR01MH113257 · NIMH · YALE UNIVERSITY · PI Alvaro Duque · 2017 to 2026
$4.3M
Research Training for Medical Students & Physician-Scientists in Child PsychiatryR25MH077823 · NIMH · YALE UNIVERSITY · PI ANDRES S MARTIN · 2006 to 2026
$4.0M
Heterogeneity of Forebrain Neural PrecursorsR01NS095654 · NINDS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HAYDAR, TARIK F, SESTAN, NENAD · 2015 to 2019
$3.4M
1/3 Integrative Genomic Analysis of Human Brain Development and AutismR01MH110926 · NIMH · YALE UNIVERSITY · PI SESTAN, NENAD · 2016 to 2019
$3.2M
Identification of Genetic and Molecular Bases of Derived Phenotypes in Primate Brain DevelopmentR01HG010898 · NHGRI · YALE UNIVERSITY · PI SANTPERE BARO, GABRIEL, SESTAN, NENAD · 2020 to 2023
$2.2M
Association of gene expression and brain connectivity in human cerebral cortex development and adulthoodR01MH129981 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI HUANG, HAO · 2022 to 2025
$1.8M
Cholinergic Contribution to Circuits Guiding Behavioral Responses to StressorsRF1MH077681 · NIMH · YALE UNIVERSITY · PI YANN Sebastien MINEUR, Marina R Picciotto · 2026 to 2026
$838k
NHGRI NIH HHS R01 HG010898NIMH NIH HHS P50 MH106934NIMH NIH HHS R01 MH077681NIMH NIH HHS R01 MH092535NIMH NIH HHS R01 MH110926NIMH NIH HHS R01 MH113257NIMH NIH HHS R01 MH125333NIMH NIH HHS R01 MH129981NIMH NIH HHS R25 MH077823NIMH NIH HHS RF1 MH077681NIMH NIH HHS T32 MH014276NIMH NIH HHS U01 MH116488NINDS NIH HHS F32 NS117780NINDS NIH HHS R01 NS095654
6 · The paper itself

Abstract

The ventrolateral pallial (VLp) excitatory neurons in the claustro-amygdalar complex and piriform cortex (PIR; which forms part of the palaeocortex) form reciprocal connections with the prefrontal cortex (PFC), integrating cognitive and sensory information that results in adaptive behaviours

Indexed as

AmygdalaBasal GangliaNeural PathwaysNeuronsAnimalsFemaleHumansMaleMicePrefrontal CortexSOXC Transcription FactorsTranscription Factor AP-2SOXC Transcription FactorsTranscription Factor AP-2

Identifiers

PMID39814878
PMCPMC11821539

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.