Evidence map›Paper›PMID 39816694›Full record

ArticleTheranostics2025

Transferrin-binding domain inserted-adenovirus hexon engineering enables systemic immune evasion and intratumoral T-cell activation.

Dae Hoon Lee, Youngtae Kwon, Ki Hwan Um, Jung Ki Yoo, Wootae Ha, Ki-Su Kim, Jintak Cha, Ha-Eun Cho, Kyung Sun Park, Min Jeong Kye and 1 more

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dae Hoon LeeDepartment of Pharmacology, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Youngtae KwonR&D Center of Curigin Ltd. Seoul 04778, Republic of Korea.
Ki Hwan UmDepartment of Pharmacology, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Jung Ki YooDepartment of Pharmacology, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Wootae HaR&D Center of Curigin Ltd. Seoul 04778, Republic of Korea.
Ki-Su KimDepartment of Pharmacology, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Jintak ChaDepartment of Pharmacology, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.
Ha-Eun ChoDepartment of Laboratory Medicine, Kyung Hee University College of Medicine, Kyung Hee University Medical Center, Seoul 02447, Republic of Korea.
Kyung Sun ParkDepartment of Laboratory Medicine, Kyung Hee University College of Medicine, Kyung Hee University Medical Center, Seoul 02447, Republic of Korea.
Min Jeong KyeR&D Center of Curigin Ltd. Seoul 04778, Republic of Korea.
Jin Woo ChoiDepartment of Pharmacology, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenoviridaeCapsid ProteinsCD8-Positive T-LymphocytesImmune EvasionTransferrinAnimalsAntibodies, NeutralizingAntibodies, ViralCell Line, TumorFemaleGenetic VectorsHumansLymphocyte ActivationMiceOncolytic VirotherapyOncolytic VirusesAntibodies, NeutralizingAntibodies, ViralCapsid Proteinshexon capsid protein, AdenovirusTransferrinadenovirusantibody evading viral vectorhexon engineered adenovirusoncolytic virussystemic injectable viral vector

Identifiers

PMID39816694
PMCPMC11729563

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.