Evidence map›Paper›PMID 39816833›Full record

ArticleFrontiers in parasitology2023

TUSK: a ubiquitin hydrolase complex modulating surface protein abundance in trypanosomes.

Kayo Yamada, Ning Zhang, Farzana K Yaqub, Martin Zoltner, Mark C Field

Abstract read
In one paragraph

Article in Frontiers in parasitology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kayo YamadaSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.
Ning ZhangSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.
Farzana K YaqubSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.
Martin ZoltnerSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.
Mark C FieldSchool of Life Sciences, University of Dundee, Dundee, United Kingdom.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Control of protein levels is vital to cellular homeostasis, for maintaining a steady state, to coordinate changes during differentiation and other roles. In African trypanosomes surface proteins contribute to immune evasion, drug sensitivity and environmental sensing. The trypanosome surface is dominated by the GPI-anchored variant surface glycoprotein, but additional GPI-anchored and

Indexed as

cullin complexdeubiquitinasedrug sensitivitysurface proteinstraffickingtrypanosomesubiquitylation

Identifiers

PMID39816833
PMCPMC11732084

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.